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/ N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺

N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 {[allProObj[0].p_purity_real_show]}

货号：A362737 同义名： N-feruloyltyramine; Moupinamide

N-trans-Feruloyltyramine是一种天然生物碱，具有抗氧化活性。它能够减轻 H2O2 诱导的细胞内 ROS 生成并减少细胞凋亡，潜力用于氧化应激相关的神经退行性疾病和癌症研究。

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 化学结构 CAS号：66648-43-9
N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 化学结构
CAS号：66648-43-9
N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 3D分子结构
CAS号：66648-43-9
N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 化学结构 CAS号：66648-43-9
N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 3D分子结构 CAS号：66648-43-9
规格 价格 会员价 库存 数量
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N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 纯度/质量文件 产品仅供科研

货号：A362737 标准纯度： {[allProObj[0].p_purity_real_show]}
批次查询： 批次纯度:

全球学术期刊中引用的产品

• Nature, 2025, 645, 793-800. Ambeed. [ A201204 , A444152 , A344107 , A952055 ]
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• Sig. Transduct. Target. Ther., 2025, 10, 257. Ambeed. [ A104916 ]
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产品名称 COX ↓ COX-1 ↓ COX-2 ↓ 其他靶点 纯度
Piroxicam ✔ 98%
Salicylic acid ✔ 98%
Phenacetin ✔ 98%
Etodolac ✔ 99%
Flunixin meglumine ✔ 98%
Ibuprofen L-lysine ✔ 98%
Nabumetone ✔ 98%
Acemetacin ✔ 98%
Diflunisal ✔ 98%
Pranoprofen ✔ 98%
Ampiroxicam ✔ 98%
Meloxicam ✔ 98%
Sulindac ✔ 98%
Ketoprofen ✔ 98%
Mefenamic Acid ✔ 95%
Bromfenac sodium ✔ 98%
Oxaprozin ✔ 99%
Aspirin ✔ 99%
Nepafenac ✔ 98%
Zaltoprofen ✔ 99%
Salicin ✔ 98%
Suprofen ✔ 99%+
Xanthohumol ✔ 99%
Parecoxib ✔ 98%
Tolfenamic Acid +++

COX-2, IC50: 0.2 μM

 		98%
Etoricoxib ✔ 99%
Niflumic Acid ✔ 98%
Valdecoxib ++++

COX-2, IC50: 5 nM

 		99+%
Ibuprofen +

COX-1, IC50: 13 μM

 		+

COX-2, IC50: 370 μM

 		98%
Indomethacin ++

COX1, IC50: 0.28 μM

 		+

COX-2, IC50: 14 μM

 		97%
Lornoxicam ++++

COX-1, IC50: 5 nM

 		++++

COX-2, IC50: 8 nM

 		98%
Meclofenamic acid sodium ++++

COX-1, IC50: 40 nM

 		+++

COX-2, IC50: 50 nM

 		99%
Asaraldehyde ✔ 98%
Naproxen +

COX-1, IC50: 8.7 μM

 		+

COX-2, IC50: 5.2 μM

 		98%
Diclofenac Sodium Salt +++

COX-1, IC50: 60 nM

 		+++

COX-2, IC50: 200 nM

 		98%
NS-398 ++

COX-2, IC50: 3.8 μM

 		95%
Amfenac Sodium Hydrate ++

COX-1, IC50: 250 nM

 		+++

COX-2, IC50: 150 nM

 		98%+
Nimesulide +

COX-2, IC50: 26 μM

 		98%
Lumiracoxib ++

COX-1, Ki: 3 μM

 		+++

COX-2, Ki: 60 nM

 		98%
Rutaecarpine ✔ 95%
Celecoxib ++++

COX-2, IC50: 40 nM

 		98%
Carprofen ++++

canine COX2, IC50: 30 nM

 		98%
Ketorolac ++

COX-1 (human), IC50: 1.23 μM

 		++

COX-2 (human), IC50: 3.50 μM

 		98%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 生物活性

描述 N-trans-Feruloyltyramine, a natural product isolated and purified from the herbs of Cannabis sativa L., has antioxidative activity against Aβ(1-42)-induced neuronal death. NTF is likely to inhibit COX enzymes, thereby suppressing P-selectin expression on platelets, is a platelet aggregation inhibitor.

N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 参考文献

[1]Jiang Y, Yu L, Wang MH. N-trans-feruloyltyramine inhibits LPS-induced NO and PGE2 production in RAW 264.7 macrophages: Involvement of AP-1 and MAP kinase signalling pathways. Chem Biol Interact. 2015 Jun 25;235:56-62.

[2]Thangnipon W, Suwanna N, et al. Protective role of N-trans-feruloyltyramine against β-amyloid peptide-induced neurotoxicity in rat cultured cortical neurons. Neurosci Lett. 2012 Apr 4;513(2):229-32.

N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.19mL

0.64mL

0.32mL

15.96mL

3.19mL

1.60mL

31.91mL

6.38mL

3.19mL

N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 技术信息

CAS号66648-43-9
分子式C18H19NO4
分子量 313.35
SMILES Code O=C(NCCC1=CC=C(O)C=C1)/C=C/C2=CC=C(O)C(OC)=C2
MDL No. MFCD17214811
别名 N-feruloyltyramine; Moupinamide; (E)-Feruloyltyramine, Alfrutamide, Moupinamide, N-trans-Feruloyltyramine; (E)-Feruloyltyramine; Alfrutamide
运输蓝冰
InChI Key NPNNKDMSXVRADT-WEVVVXLNSA-N
Pubchem ID 5280537
存储条件

In solvent -20°C: 3-6个月 -80°C: 12个月

Pure form Keep in dark place, inert atmosphere, room temperature
溶解方案

DMSO: 105 mg/mL(335.09 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

请根据您的动物给药指南选择适当的溶解方案。
以下溶解方案都请先按照体外实验的方式配制澄清的储备液，再依次添加助溶剂：
——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议现用现配，当天使用； 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶
方案 一
方案 二
方案 三

Tags: N-trans-Feruloyltyramine | 66648-43-9 | N-feruloyltyramine | Moupinamide | Immunology/Inflammation | NF-κB | Metabolic Enzyme/Protease | Apoptosis | Reactive Oxygen Species | Apoptosis | 仅供科研使用 | AmBeed-信号通路专用抑制剂 | N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 纯度/质量文件 | N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 亚型比较 | N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 生物活性 | N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 参考文献 | N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 实验方案 | N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺 技术信息

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