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货号 产品名 纯度
A2226501 FSEN1

FSEN1是一种有效的非竞争性FSP1抑制剂,其IC50为313 nM。FSEN1通过抑制FSP1诱导癌细胞中的铁死亡,可用于癌症研究。

98%
A1007917 iFSP1

iFSP1 is a FSP1 (Ferroptosis suppressor protein 1) inhibitor.

99%+
A1361460 Takeda103A

99%+
A1155014 IKE (Imidazole ketone erastin )/咪唑酮伊拉斯汀(PUN30119)

IKE is a potent, metabolically stable inhibitor of system Xc- and inducer of ferroptosis potentially suitable for in vivo applications.

99%+
A745895 IC 86621

95%
A720858 CIL56

CIL56 acts by inducing non-apoptotic cell death, triggering cell death dependent upon the rate-limiting de novo lipid synthetic enzyme ACC1.

99%+
A1490492 SRS16-86

SRS16-86, a ferrostatin analog, is a novel third-generation inhibitor of ferroptosis. It is the first compound in this class that is stable in plasma and liver microsomes and that demonstrates high efficacy when supplied alone or in combination therapy.

98%+
A497373 4-Bromopyrene/4-溴芘

95%
A397520 Chrysosplenetin/猫眼草黄素

Chrysosplenetin, a natural product isolated and purified from the herbs of Laggera pterodonta, is a metabolic inhibitor of artemisinin.

98%
A199705 Withaferin A/醉茄素A

98%
A2421868 GPX4-IN-6

GPX4-IN-6是一种GPX4的共价抑制剂,其IC50为0.12μM。它诱导了铁死亡,可用于三阴性乳腺癌(TNBC)的研究。

98%
A1210149 SRS11-92

97%
A1465562 Erastin2

98%
A2628347 icFSP1

98%
A365685 Arteannuin B/青蒿素B

Arteannuin B, a biogenetic precursor of artemisinin found in the herb artemisia annua, is active against different bacteria and certain fungal species with potential antimalarial and antitumor activities.

99%+
A340728 Butylated hydroxytoluene/2,6-二叔丁基对甲酚

Butylated hydroxytoluene is an antioxidant widely used in foods and in food-related products. Butylated hydroxytoluene is a Ferroptosis inhibitor.

98%
A2192877 CWI1-2

98%
A149084 Akebia saponin D/木通皂苷PK

Asperosaponin VI, a natural product isolated and purified from the root of Dipsacus asperoides, may exert apoptosis-inducing activity via induction of apoptosis through activation chiefly via the nitric oxide and apoptosis-related p53 and Bax gene expression.

99%+
A2273170 ROS-generating agent 1

99%+
A120662 Liproxstatin-1/利普司他丁-1

Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM.

99%+
产品名 Ferroptosis 其他靶点 纯度
Ferrostatin-1 ++

Ferroptosis, EC50: 60 nM

98%
Liproxstatin-1 +++

ferroptosis, IC50: 22 nM

99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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