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货号 产品名 纯度
A510773 现货 Vedaprofen/维达洛芬

Vedaprofen (Quadrisol) 是一种选择性 COX-1 非甾体抗炎药(NSAID),抑制血清 TxB2 和渗出物 PGE2。Vedaprofen 是大肠杆菌滑动夹(SC)抑制剂,IC50 为 222 μM。

98%
A854334 现货 Ginsenoside C-K/人参皂苷 CK

Ginsenoside C-K (Standard) 是 Ginsenoside C-K 的分析标准品。Ginsenoside C-K 是一种 Ginsenoside Rb1 的细菌代谢物。Ginsenoside C-K 通过抑制诱生型一氧化氮合酶 (iNOS) 和 COX-2 来发挥抗炎作用。在人肝微粒体中,Ginsenoside C-K 抑制 CYP2C9 和 CYP2A6 活性,IC50 分别为 32.0±3.6 μM和 63.6±4.2 μM。

98+%
A456389 现货 Macelignan/安五脂素

Anwuligan 是从五味子(Schisandra chinensis)果实中分离和纯化的天然产物,具有对抗氧化应激和神经炎症的神经退行性疾病的治疗潜力。

99%+
A934783 现货 meso-Dihydroguaiaretic acid

Dihydroguaiaretic acid,从三白草的果实中分离,具有抗癌活性。

98%
A113156 现货 NS-398

NS-398是一种非甾体抗炎剂,具有镇痛和退热作用。它选择性抑制前列腺素G/H合酶2/环氧合酶2(COX-2)的活性,IC50值为3.8 μM,而对COX-1在100 μM时没有影响。

98%
A1209995 现货 GW-406381

99%
A1354460 现货 Nabumetone-d3

98% 98%atom%D
A457768 现货 Isoxicam/伊索昔康

98%+
A417388 现货 Rosmanol

95%
A446723 现货 Dexketoprofen (trometamol)/右酮洛芬氨丁三醇

97%
A128141 现货 Ermanin/堪非醇3,4'-二-O-甲醚

Ermanin, a natural product isolated and purified from the herb of Tanacetum parthenium with anti-poliovirus activity, has a high deterrent activity at 40 ppm against Dione juno larvae.

98%+
A450261 现货 Suxibuzone/琥布宗

Suxibuzone is a drug used for joint and muscular pain, is a prodrug of the non steroidal anti inflammatory drug Phenylbutazone.

98%
A799725 现货 1-Hydroxy-ibuprofen

95%
A151994 现货 Ethyl Laurate/月桂酸乙酯

99%
A688300 现货 Columbin/古伦宾

Columbin is a diterpenoid furanolactone with anti-inflammation activity.

98%
A989023 现货 4-Vinylsyringol

97% (stabilized with TBC)
A857431 现货 Keracyanin chloride

98%
A362737 现货 N-trans-Feruloyltyramine/N-反式-阿魏酰酪胺

N-trans-Feruloyltyramine, a natural product isolated and purified from the herbs of Cannabis sativa L., has antioxidative activity against Aβ(1-42)-induced neuronal death. NTF is likely to inhibit COX enzymes, thereby suppressing P-selectin expression on platelets, is a platelet aggregation inhibitor.

98%
A100810 现货 Loxoprofen sodium/洛索洛芬钠

Loxoprofen Sodium is a non-selective cyclooxygenase inhibitor, a nonsteroidal anti-inflammatory drug (NSAID) working by reducing the synthesis of prostaglandins from arachidonic acid.

97%
A142956 现货 Bromfenac sodium/溴芬酸钠

Bromfenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.

98%
产品名 COX COX-1 COX-2 其他靶点 纯度
Piroxicam 98%
Salicylic acid 98%
Phenacetin 98%
Etodolac 99%
Flunixin meglumine 98%
Ibuprofen L-lysine 99%
Nabumetone 98%
Acemetacin 98%
Diflunisal 98%
Pranoprofen 98%
Ampiroxicam 98%
Meloxicam 98%
Sulindac 98%
Ketoprofen 98%
Mefenamic Acid 95%
Bromfenac sodium 98%
Oxaprozin 99%
Aspirin 99%
Nepafenac 98%
Zaltoprofen 97%
Salicin 98%
Suprofen 99%+
Xanthohumol 99%
Parecoxib 98%
Tolfenamic Acid +++

COX-2, IC50: 0.2 μM

98%
Etoricoxib 99%
Niflumic Acid 98%
Valdecoxib ++++

COX-2, IC50: 5 nM

99+%
Ibuprofen +

COX-1, IC50: 13 μM

+

COX-2, IC50: 370 μM

98%
Indomethacin ++

COX1, IC50: 0.28 μM

+

COX-2, IC50: 14 μM

97%
Lornoxicam ++++

COX-1, IC50: 5 nM

++++

COX-2, IC50: 8 nM

98%
Meclofenamic acid sodium ++++

COX-1, IC50: 40 nM

+++

COX-2, IC50: 50 nM

99%
Rofecoxib ++++

COX-2, IC50: 18 nM

98%
Asaraldehyde 98%
Naproxen +

COX-1, IC50: 8.7 μM

+

COX-2, IC50: 5.2 μM

98%
Diclofenac Sodium Salt +++

COX-1, IC50: 60 nM

+++

COX-2, IC50: 200 nM

98%
NS-398 ++

COX-2, IC50: 3.8 μM

98%
Amfenac Sodium Hydrate ++

COX-1, IC50: 250 nM

+++

COX-2, IC50: 150 nM

97%
Nimesulide +

COX-2, IC50: 26 μM

98%
Lumiracoxib ++

COX-1, Ki: 3 μM

+++

COX-2, Ki: 60 nM

98%
Rutaecarpine 95%
Celecoxib ++++

COX-2, IC50: 40 nM

98%
Carprofen ++++

canine COX2, IC50: 30 nM

98%
Ketorolac ++

COX-1 (human), IC50: 1.23 μM

++

COX-2 (human), IC50: 3.50 μM

98%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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