N-trans-Feruloyltyramine

产品说明书

Print
Chemical Structure| 66648-43-9 同义名 : N-feruloyltyramine; Moupinamide; (E)-Feruloyltyramine, Alfrutamide, Moupinamide, N-trans-Feruloyltyramine; (E)-Feruloyltyramine; Alfrutamide
CAS号 : 66648-43-9
货号 : A362737
分子式 : C18H19NO4
纯度 : 99%
分子量 : 313.35
MDL号 : MFCD17214811
存储条件：

Pure form Keep in dark place, inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(335.09 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 N-trans-Feruloyltyramine, a natural product isolated and purified from the herbs of Cannabis sativa L., has antioxidative activity against Aβ(1-42)-induced neuronal death. NTF is likely to inhibit COX enzymes, thereby suppressing P-selectin expression on platelets, is a platelet aggregation inhibitor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.19mL

0.64mL

0.32mL

15.96mL

3.19mL

1.60mL

31.91mL

6.38mL

3.19mL
参考文献

[1]Jiang Y, Yu L, Wang MH. N-trans-feruloyltyramine inhibits LPS-induced NO and PGE2 production in RAW 264.7 macrophages: Involvement of AP-1 and MAP kinase signalling pathways. Chem Biol Interact. 2015 Jun 25;235:56-62.

[2]Thangnipon W, Suwanna N, et al. Protective role of N-trans-feruloyltyramine against β-amyloid peptide-induced neurotoxicity in rat cultured cortical neurons. Neurosci Lett. 2012 Apr 4;513(2):229-32.