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Marmin {[allProObj[0].p_purity_real_show]}

货号：A237941

Marmin, a natural product isolated and purified from the herbs of Citrus maxima with potent anti-ulcer, antibacterial, fungicidal, and algicidal properties, can inhibit contraction of the guinea-pig tracheal smooth muscle, especially by interfering histamine receptor, inhibiting the histamine release from mast, inhibiting intracellular Ca2+ release from the intracellular store and the Ca2+ influx through voltage-dependent Ca2+ channels, is potential to develop as antihistamine agents, especially as histamine H1 receptor antagonists by interacting with amino acid residues, Asp107, Lys179, Lys191, Asn198, and Trp428 of histamine H1 receptor, shows a cell-growth inhibitory effect against L1210 and K562 in vitro.

Marmin 化学结构
CAS号：14957-38-1

Marmin 3D分子结构
CAS号：14957-38-1

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Marmin 纯度/质量文件产品仅供科研

货号：A237941 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • Nature, 2025, 645, 793-800. Ambeed. [ A201204 , A444152 , A344107 , A952055 ]; • Cell, 2025, 188, (21): 5847-5861.e11. Ambeed. [ A122167 ]; • Science, 2025, 387(6729): eadp5637. Ambeed. [ A875019 ]; • Sig. Transduct. Target. Ther., 2025, 10, 257. Ambeed. [ A104916 ]; • Nat. Nanotechnol., 2025, 20, 1502-1513. Ambeed. [ A243018 , A1216705 , A522597 , A125401 , A1355641 ]; 更多 >

组胺受体亚型比较
Calcium Channel 亚型比较

产品名称	H1 receptor ↓ ↑	H2 receptor ↓ ↑	H3 receptor ↓ ↑	H4 receptor ↓ ↑	Histamine receptor ↓ ↑	其他靶点	纯度
Hydroxyzine 2HCl							99+%
Cyclizine	✔						97%
Loratadine	+ B(0)AT2, IC50: 4 μM						98%
Desloratadine	++ Histamine H1 receptor, IC50: 51 nM						98%
Doxylamine succinate	✔						99%
Ebastine	✔						98%
Tripelennamine HCl	+ H1 receptor, IC50: 30 μM						98%
Meclizine 2HCl	✔						98%
Chlorpheniramine maleate	+++ Histamine H1 receptor, IC50: 12 nM						99%
Diphenhydramine HCl	✔						99%
Alcaftadine	++++ H1 receptor, pKi: 8.5	++ H2 receptor, pKi: 7.2					99%+
Fexofenadine HCl	++ Histamine H1 receptor, IC50: 246 nM						99%+
Bilastine	+++ H1 receptor, Ki: 44.15 nM						98%
Pemirolast potassium	✔						98%
Bepotastine besilate	+ Histamine H1 receptor, pIC50: 5.7						98%
Mizolastine	+++ Histamine H1 receptor, IC50: 47 nM						98%
Brompheniramine maleate	✔						98%
Carbinoxamine maleate salt	✔						99+%
Clemastine fumarate	++++ Histamine H1 receptor, IC50: 3 nM						98%
Ketotifen fumarate salt	✔						95%
Rupatadine Fumarate	++ Histamine H1 receptor, Ki: 102 nM					PAFR	98%
Famotidine		✔					97%
Roxatidine Acetate HCl		+ Histamine H2 receptor, IC50: 3.2 μM					98%
Lafutidine		✔					99%
Cimetidine		✔					98%
Nizatidine		++++ Histamine H2 receptor, IC50: 0.9 nM				AChE	98%
Ranitidine		✔					96%
Betahistine			+ Histamine H3 receptor, IC50: 1.9 μM				99%
Ciproxifan maleate			+++ Histamine H3 receptor, IC50: 9.2 nM				99%+
S 38093			++ rat H3 receptor, Ki: 1.44 μM human H3 receptor, Ki: 1.2 μM				98%
JNJ-7777120				++++ Histamine H4 receptor, Ki: 4.5 nM			99%
Azelastine HCl					✔		98%
Epinastine HCl					✔		99%
Levodropropizine					✔		97%
Cyproheptadine HCl					✔		98%
Hesperetin					✔		97%
Olopatadine HCl					✔		98%
Mianserin HCl					✔		99+%
Buclizine 2HCl					✔		95%
Latrepirdine 2HCl					✔	GluR	99%
Cetirizine 2HCl					✔		98%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

产品名称	Ca2+ channel-like protein ↓ ↑	Calcium Channel ↓ ↑	Cav 2.2 ↓ ↑	其他靶点	纯度
CDC25B-IN-2	✔			Akt	99%+
Clevidipine		✔			97%
Verapamil HCl		✔			99%
Amlodipine		✔			99%
Amlodipine maleate		✔			98%
(+)-cis-Diltiazem HCl		✔			99%
Zegocractin		++ Orai1/STIM1-mediated Ca2+ currents, IC50: 120 nM			99%+
Tanshinone IIA sulfonate sodium		✔			98%
Ulixacaltamide		++ hCaV3.2, IC50: 110 nM hCaV3.1, IC50: 50 nM			99%+
Dronedarone HCl		✔			95%
Nitrendipine		+ Calcium channel, IC50: 95 nM			98%
Efonidipine HCl monoethanolate		✔			98%
Cinnarizine		✔			98%
SEA0400		++ NCX, IC50: 33 nM		ERK,ROS,p38 MAPK	99%+
Fasudil HCl		✔		PKA,Rho	98%
ML-9		✔		Akt,MLCK	99%+
Flunarizine 2HCl		+ Calcium channel, Ki: 68 nM			95%
Lomerizine 2HCl		✔			98%
Efonidipine		✔			98%
Levamlodipine		✔			98%
Nisoldipine		++ L-type Cav1.2, IC50: 10 nM			97%
Isradipine		✔			98%
Lacidipine		✔			98%
Lercanidipine		✔			99%
Loureirin B		✔		Potassium Channel	99%+
Tetracaine HCl		✔			98%
Manidipine		+++ Calcium channel, IC50: 2.6 nM			99%
Manidipine Dihydrochlorid		+++ Calcium channel, IC50: 2.6 nM			98%
Nicardipine		✔			99%
Wilforgine		✔			98+%
Econazole		✔			99%+
Ginsenoside Rd		✔		NF-κB	98%
Fendiline HCl		✔			98+%
Mesaconitine		✔			98%
Tetrandrine		✔			95%
Nifedipine		✔			98%
Nilvadipine		++++ Calcium channel, IC50: 0.03 nM			95%
Barnidipine		++++ [³H]nitrendipine, Ki: 0.21 nM			95+%
Azelnidipine		✔			97%
Levetiracetam		✔			98%
Nimodipine		✔			95%
Benidipine HCl		✔			98%
Pinaverium bromide		✔			98%
Pranidipine		✔			99%
NP118809		+ N-type Ca2+ channel, IC50: 0.11 μM L-type calcium channel, IC50: 12.2 μM			95%
Amlodipine Besylate		+++ Calcium channel, IC50: 1.9 nM			97%
Cilnidipine		✔			99%
Cinepazide Maleate		✔			99% (HPLC)
Terfenadine		✔			98%
YM-58483		✔			99%+
Amiloride HCl		✔			98%
Ranolazine		✔			98%
Praeruptorin A		✔		Akt,p38 MAPK	98%
Ranolazine 2HCl		✔			98%
Felodipine		++++ L-type calcium channel, IC50: 0.15 nM			98%
PD173212		+++ N-type Ca2+ channel, IC50: 36 nM			98%
Levamlodipine besylate		✔			97%
Carboxyamidotriazole Orotate		✔			98%
IGS-1.76		✔			98+%
WH-4-023		++++ Cav 2.2, IC50: 0.001 μM	++++ Cav 2.2, IC50: 0.001 μM		99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

Marmin 生物活性

描述

Marmin 参考文献

[1]Nugroho AE, Anas Y, et al. Effects of marmin, a compound isolated from Aegle marmelos Correa, on contraction of the guinea pig-isolated trachea. Pak J Pharm Sci. 2011 Oct;24(4):427-33.

[2]Takase H, Yamamoto K, et al. Pharmacological profile of gastric mucosal protection by marmin and nobiletin from a traditional herbal medicine, Aurantii fructus immaturus. Jpn J Pharmacol. 1994 Sep;66(1):139-47.

Marmin 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

3.01mL

0.60mL

0.30mL

15.04mL

3.01mL

1.50mL

30.09mL

6.02mL

3.01mL

Marmin 技术信息

CAS号	14957-38-1
分子式	C₁₉H₂₄O₅
分子量	332.39
SMILES Code	O=C1C=CC2=CC=C(OC/C=C(C)/CC[C@@H](O)C(C)(O)C)C=C2O1
MDL No.	MFCD06796693

别名
运输	蓝冰

存储条件	In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, 2-8°C

Marmin {[allProObj[0].p_purity_real_show]}

Marmin 纯度/质量文件产品仅供科研

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Marmin {[allProObj[0].p_purity_real_show]}

Marmin 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

Marmin 质控信息

Marmin 生物活性

Marmin 参考文献

Marmin 实验方案

Marmin 技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

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热门区域

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Marmin 纯度/质量文件产品仅供科研