GSK189254A 是一种强效且选择性的组胺 H3 受体拮抗剂，人类和大鼠 H3 受体的 pKi 值分别为 9.59-9.90 和 8.51-9.17。

VUF10460 是一种非咪唑类组胺 H4 受体激动剂，对大鼠 H4 受体的结合具有 pKi 值为 7.46。

Latrepirdine dihydrochloride是一种神经活性化合物，对组胺能、α-肾上腺素能和 5-羟色胺能受体具有拮抗活性。Latrepirdine 刺激淀粉样前体蛋白 (APP) 的降解代谢和 β-淀粉样蛋白 (Aβ) 的分泌。

Lodoxamide tromethamine is used as an ophthalmic solution that specially applying to the eye.

Brompheniramine maleate is an antagonist of histamine H1 receptors.

Lodoxamide is an agonist of GPR35.

Decloxizine is a histamine 1 receptor antagonist.

Bavisant is a highly selective, orally active antagonist of the human H3 receptor with a mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD.

S 38093 is a brain-penetrant antagonist/inverse agonist of H3 receptors.

Tripelennamine HCl is an antagonist of H1-receptor that used as a psychoactive drug with antipruritic activity.

Mianserin HCl is inverse agonist of H1 receptor and can be act as a psychoactive agent of the tetracyclic antidepressant.

Roxatidine acetate HCl is a slective antagonist of histamin H2 receptor.

Ciproxifan maleate is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes.

Emedastine is a potent, high affinity histamine H1-receptor-selective antagonist with Ki of 1.3 ±0.1 nM for H1-receptors while considerably weaker at H2- (Ki = 49,067 ± 11,113 nM) and H3-receptors (Ki = 12,430 ± 1,282 nM).