货号:A155972
同义名:
柳胺苄心定
/ AH-5158 hydrochloride; Sch-15719W
Laβlol HCl is a third generation selective α-1-adrenergic antagonist and non-selective β-adrenergic antagonist, used to treat high blood pressure.
规格 | 价格 | 会员价 | 库存 | 数量 | |||
---|---|---|---|---|---|---|---|
{[ item.pr_size ]} |
{[ getRatePrice(item.pr_rmb, 1,1) ]} {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ suihuo_tips(item.pr_tag_price) ]} |
{[ getRatePrice(item.pr_rmb, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,1) ]} {[ suihuo_tips(item.pr_tag_price) ]} |
{[ getRatePrice(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_tag_price) ]} | {[ getRatePrice(item.pr_rmb_sale, 1,1) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate) ]} | 现货 | 1周 咨询 | - + |
快速发货 顺丰冷链运输,1-2 天到达
品质保证
技术支持
免费溶解
产品名称 | Adrenergic Receptor ↓ ↑ | α-adrenergic receptor ↓ ↑ | β-adrenergic receptor ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ivabradine HCl | ✔ | 98% | |||||||||||||||||
Maprotiline HCl | ✔ | 98% | |||||||||||||||||
Cisatracurium besylate | ✔ | 96% | |||||||||||||||||
Yohimbine HCI | ✔ | 99+% | |||||||||||||||||
BMY 7378 |
++
α2C-adrenoceptor, pKi: 6.54 α1D-adrenoceptor, pKi: 5.1 |
+
β1-adrenoceptor, pIC50: 5.1 |
97% | ||||||||||||||||
Asenapine maleate |
++++
α2A-adrenergic receptor, pKi: 8.9 α2B-adrenergic receptor, pKi: 8.9 |
97% | |||||||||||||||||
Piribedil |
++
adrenoceptor α2A, pKi: 7.1 adrenoceptor α2C, pKi: 7.2 |
98% | |||||||||||||||||
Prazosin HCl | ✔ | 95% | |||||||||||||||||
Silodosin | ✔ | 98% | |||||||||||||||||
Phenoxybenzamine HCl | ✔ | 98% | |||||||||||||||||
Labetalol HCl | ✔ | 98+% | |||||||||||||||||
Naftopidil |
+++
α1A-adrenergic receptor, Ki: 3.7 nM α1D-adrenergic receptor, Ki: 20 nM |
98% | |||||||||||||||||
Naftopidil 2HCl |
+
α1-adrenergic receptor, IC50: 0.2 μM |
99% | |||||||||||||||||
Alfuzosin HCl | ✔ | 98% | |||||||||||||||||
Terazosin HCl | ✔ | 99% | |||||||||||||||||
Atipamezole | ✔ | 95% | |||||||||||||||||
Phentolamine methanesulfonate salt | ✔ | 99% | |||||||||||||||||
Carvedilol | ✔ | 98% | |||||||||||||||||
Doxazosin mesylate | ✔ | 99% | |||||||||||||||||
Tolazoline HCl | ✔ | 98% | |||||||||||||||||
Esmolol HCl | ✔ | 95% | |||||||||||||||||
Propranolol HCl |
++
β-adrenergic receptor, IC50: 12 nM |
98% | |||||||||||||||||
Zenidolol HCl |
++++
β2-adrenergic receptor, Ki: 0.7nM β1-adrenergic receptor, Ki: 611nM |
98% | |||||||||||||||||
Acebutolol HCl | ✔ | 97+% | |||||||||||||||||
Carteolol HCl | ✔ | 98+% | |||||||||||||||||
Betaxolol | ✔ | 95% | |||||||||||||||||
Betaxolol HCl |
+
β1-adrenergic receptor, IC50: 6 μM |
97% | |||||||||||||||||
Bisoprolol | ✔ | 97% | |||||||||||||||||
Sotalol HCl | ✔ | 95+% | |||||||||||||||||
Nebivolol HCl |
+++
β1-adrenoceptor, IC50: 0.8 nM |
99% | |||||||||||||||||
Metoprolol | ✔ | 98+% | |||||||||||||||||
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 |
靶点 |
|
描述 | Labetalol hydrochloride is a mixed alpha/beta adrenergic antagonist that is used to treat high blood pressure. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT01316952 | - | Completed | - | - | |
NCT02135315 | Acute Coronary Syndrome | Not Applicable | Recruiting | December 2017 | Tunisia ... 展开 >> university of Monastir Recruiting Monastir, Tunisia, 5000 Contact: Nouirahead of departement 216073532014 semir.nouira@rns.tn Contact: Fattouma Bourguiba University Hospital +216 73 106 085 semir.nouira@rns.tn Principal Investigator: semir nouira, professor 收起 << |
NCT01688648 | Unstable Angina ... 展开 >> Coronary Artery Bypass Graft Dexmedetomidine Lidocaine Myocardial Injury Arrhythmia Blood Electrolyte Balance 收起 << | Not Applicable | Completed | - | Korea, Republic of ... 展开 >> Samsung Medical Center Seoul, Korea, Republic of, 135-710 收起 << |
计算器 | ||||
存储液制备 | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.74mL 0.55mL 0.27mL |
13.70mL 2.74mL 1.37mL |
27.41mL 5.48mL 2.74mL |
CAS号 | 32780-64-6 |
分子式 | C19H25ClN2O3 |
分子量 | 364.87 |
SMILES Code | O=C(N)C1=CC(C(O)CNC(CCC2=CC=CC=C2)C)=CC=C1O.[H]Cl |
MDL No. | MFCD00057663 |
别名 | 柳胺苄心定 ;AH-5158 hydrochloride; Sch-15719W; NSC 290312; AH 5158A; Labetalol (hydrochloride); Labetalol hydrochloride |
运输 | 蓝冰 |
InChI Key | WQVZLXWQESQGIF-UHFFFAOYSA-N |
Pubchem ID | 71412 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 Pure form Inert atmosphere, room temperature |
溶解方案 |
DMSO: 105 mg/mL(287.78 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 20 mg/mL(54.81 mM),配合低频超声助溶 以下溶解方案都请先按照体外实验的方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议现用现配,当天使用; 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶
|