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货号 产品名 纯度
A1081512 SIRT6-IN-2

95%
A1177281 SIRT-IN-2

98%
A1227429 WAY-354574

98%+
A1209872 YK-3-237

97%
A1218618 Sirtuin modulator 7

98%+
A202420 Thiomyristoyl/硫肉豆蔻酰

Thiomyristoyl is an inhibitor of Sirt2 and Sirt1 with IC50 of 28 nM, 98 μM.

99%+
A1177029 UBCS039

UBCS039 is a specific Sirtuin 6 activator which showed robust activating effects on Sirt6-dependent H3K18ac deacetylation of both full-length histone proteins and complete HeLa nucleosomes.

99%+
A896798 Sirtuin modulator 1/SRT3025盐酸

SRT3025 HCl is an orally available sirtuin modulator.

99%+
A1218609 Sirtuin modulator 3

99%+
A1165814 SRT 1720 hydrochloride

SRT1720 2HCl is a selective SIRT1 activator.

99%+
A1227212 Sirtuin modulator 5

98%+
A418458 Procyanidin C1/原花青素 C1

99%+
A566314 AK-7

AK-7 is a selective and brain-permeable SIRT2 inhibitor and is neuroprotective in Huntington disease mouse models.

99%+
A424556 CAY10602/1-(4-氟苯基)-3-(苯磺酰基)-1H-吡咯并[2,3-b]喹喔啉-2-胺

CAY10602 is a SIRT1 activator.

99%+
A303109 SIRT-IN-3/2-(苯基氨基)苯甲酰胺

97%
A197134 SirReal2

SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.

99%+
A799965 Verubulin

95%
A1145662 MDL 800

DL-800 is an allosteric and selective SIRT6 activator with EC50 of 10.3μM.

99%+
A557147 Salermide

Salermide, a reverse amide, can act as an inhibitor of sirt, especially of sirt2, with the property of inducing apoptosis of tumor cells.

98%
A318652 SRT 2183

SRT2183 is a small-molecule activator of the sirtuin subtype SIRT1.

99%
产品名 SIRT1 SIRT2 SIRT3 SIRT5 SIRT6 SIRT7 Sirtuin 其他靶点 纯度
Selisistat ++++

SIRT1, IC50: 38 nM

99%+
Resveratrol 98%
Inauhzin p53 99%+
Suramin sodium salt +++

SirT1, IC50: 297 nM

++

SirT5, IC50: 22 μM

99%+
Salermide 98%
Quercetin Dihydrate 95%
Sirtinol +

SIRT1, IC50: 131 μM

++

SIRT2, IC50: 38 μM

98%+
AGK2 +++

SIRT2, IC50: 3.5 μM

99%+
Tenovin-3 p53 99%+
3-TYP ++++

SIRT1, IC50: 88 nM

++++

SIRT2, IC50: 92 nM

++++

SIRT3, IC50: 16 nM

95%
Tenovin-6 ++

SIRT1, IC50: 21 μM

++

SIRT2, IC50: 10 μM

+

SIRT3, IC50: 67 μM

p53 99%+
SirReal2 +++

SIRT2, IC50: 140 nM

99%+
Thiomyristoyl ++++

SIRT2, IC50: 28 nM

99%+
Et-29 98%
OSS_128167 +

SIRT1, IC50: 1578 μM

+

SIRT2, IC50: 751 μM

+

SIRT6, IC50: 89 μM

99%+
SIRT7 inhibitor 97491 +++

SIRT7, IC50: 325 nM

97%
Nicotinamide 99+%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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