CC-401 HCl is a selective and ATP-competitive JNK inhibitor with Ki values ranging in 25-50 nM.

SP 600125, negative control是 SP 600125 的烷基衍生物，作为阴性对照用于研究。其不具显著的 JNK 抑制活性，因此用于确认 SP 600125 对 JNK（c-Jun N-terminal kinase）的特异性抑制效果。

CC-90001是一种有效、选择性和口服活性的 c-Jun N 末端激酶 (JNK) 抑制剂，在基于细胞的模型中显示出对 JNK1 的选择性是 JNK2 的 12.9 倍，适用于特发性肺纤维化的研究。

AS-602801 is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.

DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.

AEG 3482 is an inhibitor of c-jun N-terminal kinase (JNK) signaling.

BI-78D3 is a selective and competitive JNK inhibitor with IC50 of 280 nM.

JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively.

AS-601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK) (hJNK1: IC50=150nM, hJNK2: IC50=220nM and hJNK3: IC50=70 nM), has neuroprotective properties.

JNK-IN-7 is a potent inhibitor for JNK all isoforms with IC50 values of 1.5, 2 and 0.7 nM for JNK1, JNK2 and JNK3, respectively.

Isovitexin, a natural product isolated and purified from the seeds of Vitex trifolia L., exhibits a potential antioxidant activity, shows a strong antihyperglycemic action, and inhibits α-glucosidase in vivo.

TCS JNK 5a是JNK3的有效抑制剂，其pIC50为6.7。它还抑制JNK2，其pIC50为6.5。

CC-930 is a selective ATP-competitive JNK inhibitor with IC50 values of 61nM, 5nM and 5nM for JNK1, 2 and 3, respectively.

IQ-1S Free Acid is a selective JNK3 inhibitor with IC50 value of 87 nM, with less potency against JNK 1/2 with IC50 values of 390/360nM.

8-Hydroxyefavirenz是 Efavirenz 的主要代谢物，通过 JNK 和 BimEL 依赖机制诱导人原代肝细胞的凋亡 (apoptosis)。该化合物适用于癌症研究，特别是在探讨肿瘤细胞死亡机制中具有应用潜力。

Selective JNK inhibitor

Metronidazole-d4是氘代的甲硝唑 (Metronidazole)，一种硝基咪唑类抗生素，对厌氧菌和原生动物有效。

IQ 3 is a selective JNK3 inhibitor with Kd of 66 nM.

Auraptene is a natural product isolated and purified from the peel of Poncirus trifoliata with anti-tumor and anti-oxidant activity. Auraptene-mediated activation of JNK may contribute to the production of Aβ by promoting γ-secretase activity.

3,6-Dihydroxyflavone是一种具有抗癌活性的黄酮类化合物，通过激活半胱天冬酶级联反应和切割聚（ADP-核糖）聚合酶（PARP），诱导细胞凋亡，同时增加细胞内氧化应激和脂质过氧化。