Mulberroside A | Tyrosinase Inhibitor | AmBeed-信号通路专用抑制剂

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Mulberroside A/桑皮苷A {[allProObj[0].p_purity_real_show]}

货号：A400379

Mulberroside A是白桑根皮提取物中的主要抗酪氨酸酶活性成分。

Mulberroside A/桑皮苷A 化学结构
CAS号：102841-42-9

Mulberroside A/桑皮苷A 3D分子结构
CAS号：102841-42-9

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Mulberroside A/桑皮苷A 纯度/质量文件产品仅供科研

货号：A400379 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: • Nature, 2025, 645, 793-800. Ambeed. [ A201204 , A444152 , A344107 , A952055 ]; • Cell, 2025. Ambeed. [ A122167 ]; • Science, 2025, 387(6729): eadp5637. Ambeed. [ A875019 ]; • Sig. Transduct. Target. Ther., 2025, 10, 257. Ambeed. [ A104916 ]; • Nat. Nanotechnol., 2025. Ambeed. [ A243018 , A1216705 , A522597 , A125401 , A1355641 ]; 更多 >

酪氨酸酶亚型比较

产品名称	diphenolase ↓ ↑	monophenolase ↓ ↑	tyrosinase ↓ ↑	纯度
Hexylresorcinol	+++ diphenolase, IC50: 0.85 μM	++ monophenolase, IC50: 1.24 μM	+++ diphenolase, IC50: 0.85 μM monophenolase, IC50: 0.85 μM	99%+
Aloin			✔	98% (mixture of A&B)
Arbutin			+ tyrosinase, IC50: 1.09 mM	98%
Monobenzone			✔	98%
Deoxyarbutin			++++ tyrosinase, IC50: 50 nM	98%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

Mulberroside A/桑皮苷A 生物活性

靶点	JNK
描述	Mulberroside A, the major active anti-tyrosinase compound in the root bark extract of Morus alba L.

Mulberroside A/桑皮苷A 细胞实验

Cell Line Murine peritoneal macrophages Human hepatic stellate cells LX-2 Morus alba root culture Morus alba root culture Morus alba root culture	Concentration	Treated Time	Description	References
Murine peritoneal macrophages	20 or 40 μM	24 hours	To evaluate the effect of Mulberroside A on macrophage activation. Results showed that MulA treatment significantly reduced the mRNA levels of pro-inflammatory cytokines TNF-α, IL-6, and IL-1β in LPS-stimulated macrophages.	Food Sci Nutr. 2023 Mar 31;11(6):3433-3441
Human hepatic stellate cells LX-2	20 or 40 μM	24 hours	To evaluate the effect of Mulberroside A on the proliferation and activation of LX-2 cells. Results showed that MulA treatment had no significant impact on LX-2 cell proliferation or the mRNA levels of collagen I and ACTA2.	Food Sci Nutr. 2023 Mar 31;11(6):3433-3441
Morus alba root culture	200 µM MJ and 2 mg/mL YS	24 hours	Investigated the effect of elicitors on stilbene accumulation, finding the highest accumulation of Mulberroside A after 24 hours of co-treatment with MJ and YS.	Bioprocess Biosyst Eng. 2021 Apr;44(4):653-660
Morus alba root culture	19.0 mg/g	10 days	Studied the effect of precursor feeding on stilbene accumulation, finding the highest accumulation of Mulberroside A after 10 days of TYR feeding.	Bioprocess Biosyst Eng. 2021 Apr;44(4):653-660
Morus alba root culture	3 g/flask	4 weeks	Investigated the effect of root density on growth and stilbene accumulation, finding the highest accumulation of Mulberroside A at 3 g/flask initial inoculum density.	Bioprocess Biosyst Eng. 2021 Apr;44(4):653-660

Mulberroside A/桑皮苷A 动物实验

Species C57BL/c mice Rats	Animal Model CCl4-induced liver fibrosis model	Administration	Dosage	Frequency	Description	References
C57BL/c mice	CCl4-induced liver fibrosis model	Intragastric administration	20 or 40 mg/g	Three times a week for 4 weeks	To evaluate the effect of Mulberroside A on CCl4-induced liver fibrosis. Results showed that MulA treatment significantly alleviated liver injury and fibrosis, reduced collagen deposition, and suppressed pro-inflammatory cytokine expression.	Food Sci Nutr. 2023 Mar 31;11(6):3433-3441
Rats		Oral	39.5 μg/kg	Single dose	Mulberroside A was not detected in rat plasma after oral administration of Naoxintong capsule	Evid Based Complement Alternat Med. 2017;2017:9057238

Mulberroside A/桑皮苷A 参考文献

[1]Li Y, Huang L, et al. Mulberroside A suppresses PXR-mediated transactivation and gene expression of P-gp in LS174T cells. J Biochem Mol Toxicol. 2017 May;31(5).

[2]Inyai C, Komaikul J, et al. Development of a Rapid Immunochromatographic Strip Test for the Detection of Mulberroside A. Phytochem Anal. 2015 Nov-Dec;26(6):423-7.

Mulberroside A/桑皮苷A 实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

1.76mL

0.35mL

0.18mL

8.79mL

1.76mL

0.88mL

17.59mL

3.52mL

1.76mL

Mulberroside A/桑皮苷A 技术信息

CAS号	102841-42-9
分子式	C₂₆H₃₂O₁₄
分子量	568.52
SMILES Code	O[C@H]([C@@H](O)[C@@H]1O)[C@@H](O[C@@H]1CO)OC2=CC(/C=C/C(C=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)=C4)=C4O)=CC(O)=C2
MDL No.	MFCD16294844

别名
运输	蓝冰
InChI Key	HPSWAEGGWLOOKT-VUNDNAJOSA-N
Pubchem ID	6443484

存储条件

In solvent -20°C: 3-6个月 -80°C: 12个月

Pure form Keep in dark place, sealed in dry, store in freezer, under -20°C

溶解方案

细胞实验：

DMSO: 105 mg/mL(184.69 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

动物实验：请根据您的动物给药指南选择适当的溶解方案。
以下溶解方案都请先按照体外实验的方式配制澄清的储备液，再依次添加助溶剂：
——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议现用现配，当天使用；以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

方案一

方案二

方案三

配制的工作液建议现用现配，短期内尽快用完。以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶。

方案一

Mulberroside A/桑皮苷A {[allProObj[0].p_purity_real_show]}

Mulberroside A/桑皮苷A 纯度/质量文件产品仅供科研

全球学术期刊中引用的产品

Mulberroside A/桑皮苷A 质控信息

Mulberroside A/桑皮苷A 生物活性

Mulberroside A/桑皮苷A 细胞实验

Mulberroside A/桑皮苷A 动物实验

Mulberroside A/桑皮苷A 参考文献

Mulberroside A/桑皮苷A 实验方案

Mulberroside A/桑皮苷A 技术信息

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Mulberroside A/桑皮苷A {[allProObj[0].p_purity_real_show]}

Mulberroside A/桑皮苷A 纯度/质量文件 产品仅供科研

全球学术期刊中引用的产品

Mulberroside A/桑皮苷A 质控信息

Mulberroside A/桑皮苷A 生物活性

Mulberroside A/桑皮苷A 细胞实验

Mulberroside A/桑皮苷A 动物实验

Mulberroside A/桑皮苷A 参考文献

Mulberroside A/桑皮苷A 实验方案

Mulberroside A/桑皮苷A 技术信息

最近浏览的产品

大规格询价

摩尔计算器

靶点

总药量计算器

工作液计算器

细胞研究

临床研究

确认信息

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