DHODH-IN-17 是一种 2-苯胺基烟酸衍生物，作为人类 DHODH 的抑制剂，IC50 为 0.40 μM。

Sodium dichloroacetate是一种代谢调节剂，靶向癌细胞的线粒体，具有抗癌活性。它通过抑制PDHK，减少肿瘤微环境中的乳酸生成，增加活性氧（ROS）产生，并促进癌细胞凋亡。此外，它还作为NKCC抑制剂发挥作用。

FX-11是一种高效、选择性、可逆和竞争性的乳酸脱氢酶A（LDHA）抑制剂，Ki值为8 μM。它能降低ATP水平，诱导氧化应激和ROS的产生，促进细胞死亡。FX-11在淋巴瘤和胰腺癌异种移植模型中显示出抗肿瘤活性。

Glycyrrhizic acid是一种三萜皂苷，作为直接的 HMGB1 拮抗剂，具有抗肿瘤和抗糖尿病活性。

(R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor with IC50s of 3 nM and 5 nM for LDHA and LDHB respectively.

ASP 9521 is a potent and selective AKR1C3 inhibitor with IC50 of 11 nM for human AKR1C3.

3-Methylpyrazole is a nitrification inhibitor of nitrification in soil.

Carbenoxolone disodium is a glucocorticoid that inhibits 11β-hydroxysteroid dehydrogenase (11-HSD) and blocks gap junction communication.

HQNO is a potent respiratory inhibitor produced by Pseudomonas aeruginosa. It is a competitive inhibitor of quinone and targets the Q-site of NDH-2.

AG-636 is a potent, reversible, selective and orally active DHODH inhibitor with IC50 value of 17nM.

Teriflunomide, the active metabolite of an approved antirheumatic drug leflunomide, is an emerging oral therapy for multiple sclerosis (MS). It reversibly inhibits dihydroorotate dehydrogenase, the rate-limiting step in the de novo synthesis of pyrimidines.

BVT 2733 is a small molecule, non-steroidal, isoform-selective inhibitor of 11beta-hydroxysteroid dehydrogenase type 1(11β-HSD1).

Penthiopyrad is a carboxamide fungicide used to control a broad spectrum of diseases on large variety of corps and inhibits fungal respiration by binding to mitochondrial respiratory complex II.

R162 is a potent inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1) and represses glioma cell growth.

Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase (DPYD), which degrades pyrimidine including 5-fluorouracil in the blood and inhibits homologous recombination.