There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Cimetidine sulfoxide (Cimetidine sulphoxide) is a metabolite of Cimetidine, which is a histamine H2-receptor antagonist. Cimetidine exhibits potential for the treatment of peptic ulcer disease and upper gastrointestinal hemorrhage [1].
体内研究
The enantiomeric profile of Cimetidine sulfoxide is analyzed in rat urine collected over 24 hours after the oral administration of Cimetidine (30 mg/kg) to male Wistar rats. The resulting enantiomeric ratio is determined to be (+/−) 57:43 [3].
体外研究
Active transport of Cimetidine across the rat small intestine is evident at lower substrate concentrations (40 and 200 μM), but becomes obscured by passive transfer at higher concentrations (400 μM). Detection of Cimetidine sulfoxide occurs after certain incubation periods [2].
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