首页
/
/
/
/
Pactimibe sulfate
Pactimibe sulfate
{[allProObj[0].p_purity_real_show]}
货号：A1499803
同义名：
CS-505
Pactimibe sulfate (CS-505) 是一种 ACAT1/2 双重抑制剂，对 ACAT1 的 IC50 值为 4.9 μM，对 ACAT2 的 IC50 值为 3.0 μM。它在肝细胞中的 IC50 为 2.0 μM，在巨噬细胞中为 2.7 μM，在 THP-1 细胞中为 4.7 μM。Pactimibe sulfate 非竞争性抑制 oleoyl-CoA，Ki 为 5.6 μM，并显著抑制胆固醇酯的形成，IC50 为 6.7 μM。它具有抗动脉粥样硬化的潜力。
Pactimibe sulfate 化学结构
CAS号：608510-47-0
Pactimibe sulfate 3D分子结构
CAS号：608510-47-0
| 规格 |
价格 |
会员价
|
库存 |
数量 |
|
{[ item.pr_size ]}
|
{[ getRatePriceInt(item.pr_rmb, 1,1) ]}
{[ getRatePriceInt(item.pr_rmb_sale, 1,1) ]}
{[ suihuo_tips(item.pr_tag_price, item.pr_am) ]}
|
{[ getRatePriceInt(item.pr_rmb, 1,1) ]}
{[ getRatePriceInt(item.pr_rmb,item.pr_rate,1) ]}
{[ suihuo_tips(item.pr_tag_price, item.pr_am) ]}
|
{[ getRatePriceInt(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_tag_price, item.pr_am) ]} |
{[ getRatePrice(item.pr_rmb_sale, 1,1,item.mem_isinteger) ]}
{[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate,item.mem_isinteger) ]}
{[ getRatePrice(item.pr_rmb,1,item.mem_rate,item.mem_isinteger) ]}
|
现货 |
1周
咨询
|
-
+
|
Pactimibe sulfate 纯度/质量文件 产品仅供科研
货号：A1499803
标准纯度：
{[allProObj[0].p_purity_real_show]}
-
全球学术期刊中引用的产品
- • Nature, 2025, 645, 793-800. Ambeed.
[
A201204 ,
A444152 ,
A344107 ,
A952055
]
- • Cell, 2025. Ambeed.
[
A122167
]
- • Science, 2025, 387(6729): eadp5637. Ambeed.
[
A875019
]
- • Sig. Transduct. Target. Ther., 2025, 10, 257. Ambeed.
[
A104916
]
- • Nat. Nanotechnol., 2025. Ambeed.
[
A243018 ,
A1216705 ,
A522597 ,
A125401 ,
A1355641
]
- 更多 >
Pactimibe sulfate 质控信息
| KN-62 |
+
|
|
|
|
|
|
99% |
| KN-93 |
++
|
|
|
|
|
|
99% |
| NH125 |
|
+++
eEF-2 kinase, IC50: 60 nM
|
|
|
|
|
99%+ |
| STO-609 |
|
|
++
|
++++
|
|
|
98% |
| CID755673 |
|
|
|
|
+++
PKD2, IC50: 227 nM
PKD1, IC50: 180 nM
|
|
99%+ |
| CRT0066101 2HCl |
|
|
|
|
++++
PKD2, IC50: 2 nM
PKD1, IC50: 1 nM
|
|
99%+ |
|
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
|
| Penfluridol |
+
Dopamine receptor, Ki: 1.6 μM
|
|
|
|
|
|
|
|
98% |
| Ansofaxine HCl |
++
Dopamine receptor, IC50: 491 nM
|
|
|
|
|
|
|
|
99% |
| Tetrahydroberberine |
|
+
|
|
|
|
|
|
|
98+% |
| Prochlorperazine Maleate |
|
✔
|
|
|
|
|
|
|
98% (HPLC) |
| Olanzapine |
|
✔
|
|
|
|
|
|
|
99+% |
| Trifluoperazine |
|
++++
Dopamine D2 receptor, IC50: 1.1 nM
|
|
|
|
|
|
|
98% |
| Ropinirole HCl |
|
++
|
|
|
|
|
|
|
99% |
| Lurasidone |
|
++++
|
|
|
|
|
|
|
98% |
| Levosulpiride |
|
✔
|
|
|
|
|
|
|
99+% |
| Pridopidine |
|
✔
|
|
|
|
|
|
|
95% |
| Metoclopramide |
|
✔
|
|
|
|
|
✔
|
|
99+% |
| Molindone HCl |
|
✔
|
|
|
|
|
|
|
99% |
| Sulpiride |
|
✔
|
|
|
|
|
|
|
99+% |
| Perospirone |
|
++++
|
|
|
|
|
|
|
99% |
| Perospirone HCl |
|
++++
|
|
|
|
|
|
|
99% |
| Phenothiazine |
|
✔
|
|
|
|
|
|
|
98% |
| Pimozide |
+
Dopamine D1 receptor, Ki: 6600 nM
|
+++
Dopamine D2 receptor, Ki: 3.0 nM
|
++++
Dopamine D3 receptor, Ki: 0.83 nM
|
|
|
|
|
|
98% |
| Rotundine |
++
D1 receptor, IC50: 166 nM
|
+
D2 receptor, IC50: 1.47 μM
|
+
D3 receptor, IC50: 3.25 μM
|
|
|
|
|
|
98% |
| Domperidone |
|
✔
|
|
|
|
|
|
|
99+% |
| ONC206 |
|
✔
|
|
|
|
|
|
|
99% |
| Pimethixene maleate |
++
Dopamine D1 Receptor, pKi: 6.37
|
+++
Dopamine D2 Receptor, pKi: 8.19
|
|
++
Dopamine D4.4 Receptor, pKi: 7.54
|
|
|
|
|
97% |
| Loxapine succinate |
++
D1 receptor (human), Ki: 26 nM
D2 receptor (Human), Ki: 62 nM
|
++
D2 receptor (human), Ki: 24 nM
D2 receptor (bovine), Ki: 26 nM
|
|
+++
D4 receptor (human), Ki: 7.5 nM
|
|
|
|
|
98% |
| Chlorprothixene |
+++
|
+++
|
+++
|
|
+++
|
|
|
|
99% |
| SCH-23390 HCl |
++++
D1 dopamine receptor, Ki: 0.2 nM
|
|
|
|
++++
D5 dopamine receptor, Ki: 0.3 nM
|
|
|
|
98% |
| MPP+ iodide |
|
|
|
|
|
✔
|
|
|
97% |
| σ1 Receptor antagonist-1 |
|
|
|
|
|
+
|
|
|
97% |
| Benztropine mesylate |
|
|
|
|
|
++
|
|
|
98% |
| Azaperone |
|
|
|
|
|
|
✔
|
|
98% |
| Ziprasidone HCl |
|
|
|
|
|
|
✔
|
|
98+% |
| Paliperidone |
|
|
|
|
|
|
✔
|
|
98% |
| Alizapride HCl |
|
|
|
|
|
|
✔
|
|
99+% |
| Amisulpride |
|
|
|
|
|
|
✔
|
|
98% |
| Quetiapine hemifumarate |
|
|
|
|
|
|
✔
|
Adrenergic Receptor
|
98% |
| Clozapine N-oxide |
|
|
|
|
|
|
✔
|
|
99% |
|
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
|
Pactimibe sulfate 实验方案
| 计算器 |
|
| 存储液制备 |
 |
1mg |
5mg |
10mg |
|
1 mM
5 mM
10 mM
|
1.07mL
0.21mL
0.11mL
|
5.37mL
1.07mL
0.54mL
|
10.74mL
2.15mL
1.07mL
|
Pactimibe sulfate 技术信息
搜索
