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D-Tetrahydropalmatine/右旋四氢巴马汀
D-Tetrahydropalmatine/右旋四氢巴马汀
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货号：A711877
同义名：
(+)-Corydalis B; D-THP
D-Tetrahydropalmatine, a natural product isolated and purified from the barks of Phellodendron chinense Schneid, is an organic cation transporter 1 (OCT1) inhibitor, and obviously inhibits the uptake of MCT in MDCK-hOCT1 cells and isolated rat primary hepatocytes, and attenuates the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.
D-Tetrahydropalmatine/右旋四氢巴马汀 化学结构
D-Tetrahydropalmatine/右旋四氢巴马汀 3D分子结构
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D-Tetrahydropalmatine/右旋四氢巴马汀 纯度/质量文件 产品仅供科研
货号：A711877
标准纯度：
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产品说明书
全球学术期刊中引用的产品
• Nature , 2025, 645, 793-800. Ambeed. A201204 ,
A444152 ,
A344107 ,
A952055
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• Cell , 2025. Ambeed. A122167
]
• Science , 2025, 387(6729): eadp5637. Ambeed. • Sig. Transduct. Target. Ther. , 2025, 10, 257. Ambeed. A104916
]
• Nat. Nanotechnol. , 2025. Ambeed. A1216705 ,
A522597 ,
A125401 ,
A1355641
]
更多 >
D-Tetrahydropalmatine/右旋四氢巴马汀 质控信息
Penfluridol
+
Dopamine receptor, Ki: 1.6 μM
98%
Ansofaxine HCl
++
Dopamine receptor, IC50: 491 nM
99%
Tetrahydroberberine
+
98+%
Prochlorperazine Maleate
✔
98% (HPLC)
Olanzapine
✔
99+%
Trifluoperazine
++++
Dopamine D2 receptor, IC50: 1.1 nM
98%
Ropinirole HCl
++
99%
Lurasidone
++++
98%
Levosulpiride
✔
99+%
Pridopidine
✔
95%
Metoclopramide
✔
✔
99+%
Molindone HCl
✔
99%
Sulpiride
✔
99+%
Perospirone
++++
99%
Perospirone HCl
++++
99%
Phenothiazine
✔
98%
Pimozide
+
Dopamine D1 receptor, Ki: 6600 nM
+++
Dopamine D2 receptor, Ki: 3.0 nM
++++
Dopamine D3 receptor, Ki: 0.83 nM
98%
Rotundine
++
D1 receptor, IC50: 166 nM
+
D2 receptor, IC50: 1.47 μM
+
D3 receptor, IC50: 3.25 μM
98%
Domperidone
✔
99+%
ONC206
✔
99%
Pimethixene maleate
++
Dopamine D1 Receptor, pKi: 6.37
+++
Dopamine D2 Receptor, pKi: 8.19
++
Dopamine D4.4 Receptor, pKi: 7.54
97%
Loxapine succinate
++
D2 receptor (Human), Ki: 62 nM
D1 receptor (human), Ki: 26 nM
++
D2 receptor (bovine), Ki: 26 nM
D2 receptor (human), Ki: 24 nM
+++
D4 receptor (human), Ki: 7.5 nM
98%
Chlorprothixene
+++
+++
+++
+++
99%
SCH-23390 HCl
++++
D1 dopamine receptor, Ki: 0.2 nM
++++
D5 dopamine receptor, Ki: 0.3 nM
98%
MPP+ iodide
✔
97%
σ1 Receptor antagonist-1
+
97%
Benztropine mesylate
++
98%
Azaperone
✔
98%
Ziprasidone HCl
✔
98+%
Paliperidone
✔
98%
Alizapride HCl
✔
99+%
Amisulpride
✔
98%
Quetiapine hemifumarate
✔
Adrenergic Receptor
98%
Clozapine N-oxide
✔
99%
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1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
D-Tetrahydropalmatine/右旋四氢巴马汀 生物活性
描述
D-Tetrahydropalmatine, a natural product isolated and purified from the barks of Phellodendron chinense Schneid, is an organic cation transporter 1 (OCT1) inhibitor, and obviously inhibits the uptake of MCT in MDCK-hOCT1 cells and isolated rat primary hepatocytes, and attenuates the viability reduction and LDH release of the primary cultured rat hepatocytes caused by MCT.
D-Tetrahydropalmatine/右旋四氢巴马汀 参考文献
D-Tetrahydropalmatine/右旋四氢巴马汀 实验方案
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总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
2.81mL
0.56mL
0.28mL
14.07mL
2.81mL
1.41mL
28.13mL
5.63mL
2.81mL
D-Tetrahydropalmatine/右旋四氢巴马汀 技术信息
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