货号:A379804
                
                同义名:
                    
                        
                            
                                (E)-Capsaicin; Vanilloid
                            
                        
                    
                
                
                
                    
                     
                
            
Capsaicin是 TRPV1 的激动剂,在 HEK293 细胞中的 EC50 为 0.29 ± 0.05 μM,是辣椒的活性成分。
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| Type | HazMat fee for 500 gram (Estimated) | 
| Excepted Quantity | USD 0.00 | 
| Limited Quantity | USD 15-60 | 
| Inaccessible (Haz class 6.1), Domestic | USD 80+ | 
| Inaccessible (Haz class 6.1), International | USD 150+ | 
| Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ | 
| Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ | 
 
                                 
                                
                            

| 规格 | 价格 | 会员价 | 库存 | 数量 | |||
|---|---|---|---|---|---|---|---|
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| 产品名称 | Autophagy ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SBI-0206965 | +++ ULK2, IC50: 711 nM ULK1, IC50: 108 nM | 95% | |||||||||||||||||
| Hydroxychloroquine sulfate | ✔ | 99% | |||||||||||||||||
| Valproic acid sodium | ✔ | HDAC | 97% | ||||||||||||||||
| PFK-015 | ++ PFKFB3, IC50: 207 nM | 99%+ | |||||||||||||||||
| MRT68921 HCl | ++++ ULK2, IC50: 1.1 nM ULK1, IC50: 2.9 nM | 99%+ | |||||||||||||||||
| ROC-325 | ✔ | 99%+ | |||||||||||||||||
| Autophinib | +++ Autophagy, IC50: 40 nM | 99% | |||||||||||||||||
| Lys05 | ✔ | 99%+ | |||||||||||||||||
| 1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 | |||||||||||||||||||
| 描述 | Capsaicin, the active component of chili peppers, is a TRPV1 agonist with EC50 of 0.29±0.05 μM in HEK293 cells. | 
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 | 
| NCT02869867 | Localized Neuropathic Pain | Not Applicable | Recruiting | July 2019 | France ... 展开 >> CHLVO de Challans Not yet recruiting Challans, France, 85300 Contact: Natacha TAILLIEZ, Nurse CHD Vendée de la Roche sur Yon Recruiting La Roche sur Yon, France, 85925 Contact: Yves-Marie PLUCHON, PH Clinique Brétéché Not yet recruiting Nantes, France, 44000 Contact: Audrey MILLET, Nurse 收起 << | 
| NCT03472677 | Osteoarthritis, Knee | Phase 1 | Recruiting | December 1, 2018 | United Kingdom ... 展开 >> MAC Clinical Research Recruiting Manchester, United Kingdom Contact: Hannah Gornall, PhD 收起 << | 
| NCT00004316 | Interstitial Cystitis ... 展开 >> Vulvar Diseases 收起 << | Phase 1 Phase 2 | Completed | - | - | 
[1]Fokkens W, Hellings P, et al. Capsaicin for Rhinitis. Curr Allergy Asthma Rep. 2016 Aug;16(8):60.
| 计算器 | ||||
| 存储液制备 |  | 1mg | 5mg | 10mg | 
| 1 mM 5 mM 10 mM | 3.27mL 0.65mL 0.33mL | 16.37mL 3.27mL 1.64mL | 32.74mL 6.55mL 3.27mL | |
| CAS号 | 404-86-4 | 
| 分子式 | C18H27NO3 | 
| 分子量 | 305.41 | 
| SMILES Code | O=C(NCC1=CC(OC)=C(O)C=C1)CCCC/C=C/C(C)C | 
| MDL No. | MFCD00017259 | 
| 别名 | (E)-Capsaicin; Vanilloid; trans8MethylNvanillylnon6enamide; (E)N(4Hydroxy3methoxybenzyl)8ethylnon6enamide; C; PS; Capsicin; Capsicine; Qutenza | 
| 运输 | 蓝冰 | 
| InChI Key | YKPUWZUDDOIDPM-SOFGYWHQSA-N | 
| Pubchem ID | 1548943 | 
| 存储条件 | In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Inert atmosphere, 2-8°C | 
| 溶解方案 | 无水乙醇: 100 mg/mL(327.43 mM),配合低频超声助溶,注意:无水乙醇开封后,易挥发,也会吸收空气中的水分,导致溶解能力下降,请避免使用开封较久的乙醇 DMSO: 105 mg/mL(343.8 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO 以下溶解方案都请先按照体外实验的方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议现用现配,当天使用; 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶 
 
 
 
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