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货号 产品名 纯度
A122219 Brazilin/巴西苏木素

Brazilin, a red dye precursor obtained from the heartwood of several species of tropical hardwoods, inhibits the cells proliferation, promotes apoptosis, and induces autophagy through the AMPK/mTOR pathway. Brazilin shows chondroprotective and anti-inflammatory activities.

97%
A516702 Veliparib 2HCl/维利帕尼二盐酸盐

Veliparib 2HCl is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively.

99%
A130606 PF-4708671

PF-4708671 is an inhibitor of S6K1 (p70 ribosomal S6 kinase 1) with Ki and IC50 of 20 nM and 160 nM, respectively.

99%+
A702851 LY2183240

LY2183240 is a highly potent blocker of anandamide uptake (IC50 = 270 pM).

98%
A248253 JH-II-127

JH-II-127 is a brain-penetrant, potent and selective LRRK2 inhibitor with IC50 values of 2.2, 6.6 and 47.7 nM for G2019S-mutant, wild-type and A2016T-mutant LRRK2, respectively.

98%+
A326728 KJ Pyr 9

KJ Pyr 9 is a small-molecule inhibitor of MYC. The Kd of KJ Pyr 9 for MYC in vitro is 6.5±1.0 nM, as determined by backscattering interferometry.

99%+
A125109 PF-06447475

PF-06447475 is a brain-penetrant, potent and selective LRRK2 inhibitor with IC50 values of 3 nM, possessing neuroprotective activity.

99%+
A1684359 Sulfosuccinimidyl oleate sodium

98%+
A1364581 4-O-Methylbutein

98%+
A1177029 UBCS039

UBCS039 is a specific Sirtuin 6 activator which showed robust activating effects on Sirt6-dependent H3K18ac deacetylation of both full-length histone proteins and complete HeLa nucleosomes.

99%+
A1325616 (E/Z)-DMU2105

DMU2105 is a potent CYP1B1 inhibitor with IC50 value of 10nM for human CYP1B1 enzyme bound to yeast-derived microsomes (Sacchrosomes™).

99%+
A375623 Fexaramine

Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity relative to natural compounds.

99%+
A1601847 EB-42486

98%+
A164135 FAAH inhibitor 1

FAAH inhibitor 1 is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 18±8 nM.

98%+
A1177088 PFE-360

98%
A559136 N-Benzylpalmitamide/N-苄基十六烷酰胺

Macamide B is a natural product isolated and purified from the herbs of Lepidium meyenii Walp.

98%+
A1448617 SBP-7455

98%+
A922777 Gemcitabine elaidate/反油酸吉西他滨

Gemcitabine elaidate is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity.

96%
A1250770 BL-918

BL-918 is an orally active UNC-51-like kinase 1 (ULK1) activator with an EC50 of 24.14 nM. BL-918 induces cytoprotective autophagy for Parkinson's disease treatment.

99%+
A1500046 CZC-54252 HCl

98%+
产品名 Autophagy 其他靶点 纯度
SBI-0206965 +++

ULK1, IC50: 108 nM

ULK2, IC50: 711 nM

97%
Hydroxychloroquine sulfate 99%
Valproic acid sodium HDAC 97%
PFK-015 ++

PFKFB3, IC50: 207 nM

99%+
MRT68921 hydrochloride ++++

ULK1, IC50: 2.9 nM

ULK2, IC50: 1.1 nM

99%+
ROC-325 99%+
Autophinib +++

Autophagy, IC50: 40 nM

97%
Lys05 99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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