Capsaicin
产品说明书
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同义名 : | (E)-Capsaicin; Vanilloid; trans8MethylNvanillylnon6enamide; (E)N(4Hydroxy3methoxybenzyl)8ethylnon6enamide; C; PS; Capsicin; Capsicine; Qutenza |
| CAS号 : | 404-86-4 | |
| 货号 : | A379804 | |
| 分子式 : | C18H27NO3 | |
| 纯度 : | 98% | |
| 分子量 : | 305.41 | |
| MDL号 : | MFCD00017259 | |
| 存储条件： |
Pure form Inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
无水乙醇: 100 mg/mL(327.43 mM)，配合低频超声助溶，注意：无水乙醇开封后，易挥发，也会吸收空气中的水分，导致溶解能力下降，请避免使用开封较久的乙醇 DMSO: 105 mg/mL(343.8 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Capsaicin, the active component of chili peppers, is a TRPV1 agonist with EC50 of 0.29±0.05 μM in HEK293 cells. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT02869867 | Localized Neuropathic Pain | Not Applicable | Recruiting | July 2019 | France ... 展开 >> CHLVO de Challans Not yet recruiting Challans, France, 85300 Contact: Natacha TAILLIEZ, Nurse CHD Vendée de la Roche sur Yon Recruiting La Roche sur Yon, France, 85925 Contact: Yves-Marie PLUCHON, PH Clinique Brétéché Not yet recruiting Nantes, France, 44000 Contact: Audrey MILLET, Nurse 收起 << |
| NCT03472677 | Osteoarthritis, Knee | Phase 1 | Recruiting | December 1, 2018 | United Kingdom ... 展开 >> MAC Clinical Research Recruiting Manchester, United Kingdom Contact: Hannah Gornall, PhD 收起 << |
| NCT00004316 | Interstitial Cystitis ... 展开 >> Vulvar Diseases 收起 << | Phase 1 Phase 2 | Completed | - | - |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
3.27mL 0.65mL 0.33mL |
16.37mL 3.27mL 1.64mL |
32.74mL 6.55mL 3.27mL |
| 参考文献 |
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[1]Fokkens W, Hellings P, et al. Capsaicin for Rhinitis. Curr Allergy Asthma Rep. 2016 Aug;16(8):60. |