Aristolochic acid C, a metabolite of carcinogenic aristolochic acids (AAs). is a carcinogen found in aristolochia debilis. It can inhibit PLA2.

Difluprednate is a corticosteroid, approved difluprednate for the treatment of post-operative ocular inflammation and pain.

LY-311727 是一种分泌型磷脂酶 A2（sPLA2）抑制剂（对 IIA 组 sPLA2 的 IC50 < 1 μM）。sPLA2 是一种关键的促炎酶。

m-3M3FBS is a novel phospholipase C activator. It can be developed as a novel anti-leukemic agent.

ML 349 is a selective and reversible lysophospholipase 2 (LYPLA2) inhibitor with IC50 of 144 nM.

CAY10594 is a selective PLD2 inhibitor with IC50 values of 140nM and 5.1μM for PLD2 and PLD1, respectively. It strongly inhibits the invasive migration of breast cancer cells in transwell assays.

CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 12 nM.

Darapladib is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM.

Varespladib is a potent and selective human non-pancreatic secretory phospholipase A2 (sPLA) inhibitor with IC50 of 7 nM.

LCL521 2HCl, an inhibitor of acid ceramidase, shows anticancer actions of lysosomally targeted.

ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM), Exhibits 14-fold selectivity for LYPLA1 over LYPLA2, Also selective over a panel of ~30 other serine hydrolases.