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货号 产品名 纯度
A900282 Theaflavin 3,3'-digallate/茶黄素-3,3'-双没食子酸

Theaflavin-3,3'-digallate is a tea extract. Theaflavin-3,3'-digallate inhibited 3CLpro with IC50 value of 9.5μM in a fluorogenic substrate peptide assay.

99%+
A104838 Tanshinone IIA/丹参酮IIA

Tanshinone IIA is a naturally occuring cardioprotective agent which can inhibit NF-κB and AP-1 DNA binding and display antioxidant and anti-inflammatory properties. Tanshinone IIA showed inhibitory effect on PL(pro) with IC50 value of 1.6μM and less inhibitory effect on 3CLpro with IC50 value of 89.1μM.

97%
A108483 Tanshinone I/丹参酮I

Tanshinone I, an active principle isolated from the roots of Salvia miltiorrhiza (Danshen), is an inhibitor of type IIA human recombinant sPLA2 and rabbit recombinant cPLA2 with IC50s of 11 μM and 82 μM, respectively, is structurally similar to tanshinone IIA and may possess similar cytotoxic effects on tumor cells. Tanshinone I showed inhibitory effect on PL(pro) with IC50 value of 8.8μM and less inhibitory effect on 3CLpro with IC50 value of 38.7μM.

97%
A330186 Rhoifolin/野漆树苷

Rhoifolin, a natural product isolated and purified from the leaves of Turpinia arguya Seem, hows monolithic proliferation inhibitory activities against Hela, A549 and MCF-7 cell lines, and may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4. It was found to efficiently block the enzymatic activity of SARS-CoV 3CLpro.

99%+
A305232 Herbacetin

Herbacetin, a natural product isolated and purified from the herbs of Equisetum hyemale L. It was found to efficiently block the enzymatic activity of SARS-CoV 3CLpro.

99%+
A142364 Aloe emodin/芦荟大黄素

Aloe-emodin, a natural product isolated and purified from the root of Rheum palmatum L. with a specific in vitro and in vivo anti-neuroectodermal tumor activity, reduces the toxicity and ROS induced by both monomeric and oligomeric Aβ species, appears to have some protective effect not only against hepatocyte death but also on the inflammatory response subsequent to lipid peroxidation and has a strong non-carcinogenic stimulant-laxative action when applied to the skin, although it may increase the carcinogenicity of some kind of radiation. Aloe-Emodine dose-dependently inhibited cleavage activity of the 3CLpro with IC50 value of 366μM in the cell-based assay.

97%
A780751 Dieckol/二鹅掌菜酚

Dieckol exhibited SARS-CoV 3CL(pro) trans/cis-cleavage inhibitory effects with IC50 values of 2.7 and 68.1 μM, respectively. It formed extremely strong hydrogen bonds to the catalytic dyad (Cys145 and His41) of the SARS-CoV 3CL(pro).

98%
A501874 Pectolinarin/柳穿鱼叶苷

Pectolinarigenin, a natural product isolated and purified from the herbs of Cirsium japonicum DC., possesses hepatoprotective and anti-inflammatory activity.

99%+
A1257467 ML188

16-(R)-ML188 is a non-covalent SARS-CoV 3CLpro inhibitor with good enzyme and antiviral inhibitory activity.

99%+
A1324871 XP-59

97%
A1532181 Ensitrelvir

95%
A124461 Zanamivir/扎那米韦

Zanamivir is the first of two registered neuraminidase inhibitors for the treatment and prophylaxis of influenza. Zanamivir could inhibit SARS-CoV-2 3CLpro main protease.

98%
A255311 Tanshinone IIA sulfonate sodium/丹参酮IIA-磺酸钠

Tanshinone IIA sulfonate sodium is a water-soluble derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca2+entry (SOCE), and is used to treat cardiovascular disorders.

98%
A598153 Remdesivir/瑞德西韦

Remdesivir is an nucleotide-analog antiviral prodrug. Remdesivir could inhibit SARS-CoV-2 3CLpro main protease.

99%
A732241 Saquinavir Mesylate/沙奎那韦甲磺酸盐

Saquinavir mesylate is an HIV Protease inhibitor used in antiretroviral therapy. Saquinavir could inhibit SARS-CoV-2 3CLpro main protease.

98%
A238234 Hesperetin/橙皮素

Hesperetin is a flavanone extracted from the peel of citrus that exhibits inhibition of PDE4 and UGT. Hesperetin has antioxidative and anti-inflammatory effects as well. Hesperetin dose-dependently inhibited cleavage activity of the 3CLpro with IC50 value of 8.3μM in the cell-based assay.

97%
A723661 GC376 Sodium Salt

GC376 is a 3CLpro (3C-like protease) inhibitor that shows promise in treating cats with certain presentations of FIP and has opened the door to targeted antiviral drug therapy.

98%
A831392 Dihydrotanshinone I/二氢丹参酮I

Dihydrotanshinone I, a natural product isolated and purified from the roots of Salvia miltiorrhiza Bge., exhibits dose-dependent inhibition towards HLM-catalyzed propofol glucuronidation. Dihydrotanshinone I showed inhibitory effect on PL(pro) with IC50 value of 4.9μM and less inhibitory effect on 3CLpro with IC50 value of 14.4μM.

99%+
A1523532 CCF0058981

CCF0058981 is a ML300-derived, non-covalent SARS-CoV‑2 3CLpro inhibitor.

96%
A344427 Saquinavir/沙奎那韦

Saquinavir is an HIV Protease inhibitor used in antiretroviral therapy. Saquinavir could inhibit SARS-CoV-2 3CLpro main protease.

99%+
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