Mirificin (Puerarin apioside)是从葛根中提取的一种异黄酮，抑制酪氨酸酶，IC50 为 12.66 μM。

Hexylresorcinol (4-Hexylresorcinol) 是一种在植物中发现的天然化合物，具有抗菌、驱避、防腐和抗肿瘤活性。Hexylresorcinol是一种可逆的、非竞争性的α -葡萄糖苷酶抑制剂。

Sweroside, a natural product isolated and purified from the herbs of Swertia bimaculata with strong hepatoprotective, anti-osteoporotic, insulin-mimicking, and wound-healing effects, can inhibit potent melanogenesis in melan-a cells at 300uM without cytotoxicity, also decreases tyrosinase, tyrosinase-related protein-1 (TRP-1) and TRP-2 protein production in melan a cells.

2,4-Dihydroxyhydrocinnamic Acid shows tyrosinase inhibition activity when mixed with l-ascorbic acid, it is a natural product isolated and purified from the herbs of Juniperus formosana.

Methyl 3-(2,4-dihydroxyphenyl)propionate, a natural product isolated and purified from the herbs of Juniperus formosana, has inhibitory effects on tyrosinase, antioxidant ability, and lightening effect of ultraviolet B (UVB)-induced hyperpigmentation.

Kojic acid is a chelation agent produced by several species of fungi.

6-Aminofluorescein is a building block for synthesis of fluorescein and a reagent for fluorescence studies.

Aloin A, an anthracycline from aloe plants, can be used as a chemopreventive factor with antineoplastic activity. It exhibits inhibition of phosphodiesterase and tyrosinase.

Fumaric acid a reversible inhibitor of tyrosinase.

Aloesin (Aloeresin) is an active constituent of the herb aloe vera and displays anti-inflammatory activity, ultraviolet protection, and antibacterium effects. Aloesin exerts its anticancer effect through the MAPK signaling pathway[1][2].

Trifolirhizin is purified from the roots of sophora flavescens L. that possesses potential anti-inflammatory and anti-cancer activities.

3,4-Dimethoxyphenol is a plant-derived phenylpropanoid compound and can use as a whitening agent in cosmetics. 3,4-Dimethoxyphenol has tyrosinase-inhibiting activity. 3,4-Dimethoxyphenol has potent antioxidant effect isolated from the bacterial fermentation broth.

4-Butylresorcinol, a phenol derivative, is an inhibit of tyrosinase with IC50 of 11.27 μM.