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首页 / 抑制剂/激动剂 / 代谢酶 / sEH

货号 产品名 纯度
A2324213 现货 VU534

VU534是一种NAPE-PLD激动剂,其EC50为0.30 μM。它是FAAHsEH的双重抑制剂(IC50值为1.2 μM)。VU534通过NAPE-PLD依赖性途径增强巨噬细胞的吞噬作用,并在心血管代谢性疾病的研究中具有潜力。

98%
A1517316 现货 N-(3-Methoxybenzyl)stearamide

98%+
A1339021 现货 BI-1935

98%
A911625 现货 GSK2256294A

GSK2256294A is a potent, reversible, tight binding inhibitor of isolated recombinant human sEH (soluble epoxide hydrolase) (IC50 = 27 pM; t1/2 = 121 min) and displays potent inhibition against the rat (IC50 = 61 pM) and murine (IC50 = 189 pM) orthologs of sEH.

99%
A1219186 现货 EC5026

EC5026 is a first-in-class, small molecule that potently inhibits soluble Epoxide Hydrolase (sEH), a key regulatory enzyme involved in the metabolism of membrane fatty acids.

98%+
A1234842 现货 sEH inhibitor-7

99%+
A982864 现货 TPPU

TTPU is an inhibitor of epoxide hydrolase (sEH) with IC50 of 3.7 nM with anti-inflammatory and anti-atherosclerotic activities.

99%+
A1258087 现货 PTUPB

PTUPB is a novel dual COX2 and sHE (soluble epoxide hydrolase) inhibitor. Treatment with PTUPB reduced body weight, liver weight, liver triglyceride and cholesterol content, and the expression of lipolytic/lipogenic and lipid uptake related genes (Acc, Cd36, and Cidec) in HFD mice. This made it be a promising potential therapy for liver steatosis associated with obesity.

99%+
A1148766 现货 AUDA

AUDA is a potent soluble epoxide hydrolase (sEH) inhibitor with IC50s of 18 and 69 nM for the mouse and human sEH, respectively and with anti-inflammatory activity.

98%+
A1373802 现货 Diflapolin

Diflapolin is a dual inhibitor of both FLAP and sEH. It inhibited 5-LOX product formation in intact human monocytes and neutrophils with IC50 = 30 and 170 nM, respectively, and suppressed the activity of isolated sEH (IC50 = 20 nM).

97%
A1209356 现货 CUDA

CUDA is a potent inhibitor of soluble epoxide hydrolase (sEH), with IC50s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively[1]. CUDA selectively increases peroxisome proliferator-activated receptor (PPAR) alpha activity. CUDA may be valuable for the research of cardiovascular disease[2].

97%
A1209949 sEH inhibitor-1

97%
A1552326 (Rac)-EC5026

98%
A1601903 sEH inhibitor-3

98%
A1671799 sEH inhibitor-6

98%
A1671512 mEH-IN-1

98%
A2288156 sEH inhibitor-2

98%
A2420150 sEH inhibitor-11

98%
A1147194 trans-AUCB/trans-AUCB游离态

99%
A1177838 Soluble epoxide hydrolase inhibitor

99+%
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