There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Lanatoside C, a cardiac glycoside, is utilized in the management of congestive heart failure and cardiac arrhythmias. It demonstrates an IC50 of 0.19 μM against dengue virus in HuH-7 cells and is capable of inhibiting all four serotypes of dengue virus, as well as flavivirus Kunjin, alphavirus Chikungunya, Sindbis virus, and human enterovirus 71[1].[2].
体外研究
Lanatoside C shows a dose-dependent reduction in both dengue viral RNA and protein synthesis with increased concentrations. Studies on the timing of addition reveal that Lanatoside C blocks the early stages of the dengue virus replication cycle. Additionally, it effectively inhibits all four dengue virus serotypes, flavivirus Kunjin, alphavirus Chikungunya, and Sindbis virus, along with human enterovirus 71, displaying a broad-spectrum antiviral activity against various positive-sense RNA viruses[2].
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