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货号 产品名 纯度
A761523 现货 Des(benzylpyridyl) Atazanavir

Des(benzylpyridyl) Atazanavir是 Atazanavir 的代谢物,能在增强 Atazanavir 抗 HIV-1 活性中发挥作用,但同时可能增加其毒性,适用于药物相互作用和毒性研究。

95%
A1217765 现货 WAY-639418

WAY-639418是一种活性分子,适用于研究淀粉样蛋白疾病和突触核蛋白病,如阿尔茨海默病和帕金森病。该分子通过调控神经元中的蛋白聚集来研究疾病的发病机制。

99%+
A128893 现货 Nelfinavir/那非那韦

Nelfinavir is a selective and potent HIV-1 protease inhibitor used in combination with other antiviral drugs in the treatment of HIV.

99%+
A532297 现货 Methotrexate metabolite

Methotrexate metabolite(DAMPA) 是 Methotrexate 的活性代谢产物,Methotrexate是一种叶酸拮抗剂,广泛用于免疫抑制。

95%
A705666 现货 Neoechinulin A

Neoechinulin A, a natural product isolated and purified from Aspergillus chevalieri with anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, may block the phosphorylation of mitogen-activated protein kinase (MAPK) molecule p38, apoptosis signal-regulating kinase 1 (ASK-1) and nuclear translocation of nuclear factor-κB (NF-κB) p65 and p50 subunits, and ameliorate rotenone toxicity by activating a cytoprotective machinery that requires ATP and antioxidant/anti-nitration activities.

98%+
A276573 现货 Atazanavir Sulfate/阿扎那韦硫酸盐

Atazanavir Sulfate is a protease inhibitor used as an antiretroviral medication to treat and prevent HIV/AIDS.

98%
A330804 现货 Lopinavir/洛匹那韦

Lopinavir(ABT-378)是一种高效选择性的HIV-1蛋白酶抑制剂,对野生型和突变型HIV蛋白的Ki值在1.3至3.6 pM之间。其作用是阻止HIV-1的成熟,从而阻止其感染性。Lopinavir还表现出对SARS-CoV 3CLpro的抑制作用,IC50为14.2 μM。

99+%
A732241 现货 Saquinavir Mesylate/沙奎那韦甲磺酸盐

Saquinavir mesylate is an HIV Protease inhibitor used in antiretroviral therapy. Saquinavir could inhibit SARS-CoV-2 3CLpro main protease.

98%
A116353 现货 Darunavir/达芦那韦

Darunavir is a protease inhibitor which acts on the HIV aspartyl protease.

98%
A182779 现货 Atazanavir/阿扎那韦

Atazanavir is a protease inhibitor used as an antiretroviral medication to treat and prevent HIV/AIDS.

98%
A484468 现货 Fosamprenavir Calcium Salt/福沙那伟钙

Fosamprenavir Calcium the prodrug of amprenavir which is an HIV protease inhibitor with antiviral property.

99%+
A375111 现货 Amprenavir/安瑞那韦

Amprenavir is a protease inhibitor used to treat HIV infection which can form an inhibitor-enzyme complex with HIV protease.

99%+
A228436 现货 Nelfinavir Mesylate/甲磺酸奈非那韦

Nelfinavir Mesylate (AG 1343 Mesylate) 是一种高效、口服可用的HIV-1蛋白酶抑制剂(Ki=2 nM),用于HIV感染,还具有广谱抗癌作用。

99%+
A278506 现货 Tipranavir

Tipranavir, a nonpeptidic HIV protease inhibitor (NPPI), inhibits the enzymatic activity and dimerization of HIV-1 protease, exerts potent activity against multi-PI-resistant HIV-1 isolates.

99%+
A344427 现货 Saquinavir/沙奎那韦

Saquinavir is an HIV Protease inhibitor used in antiretroviral therapy. Saquinavir could inhibit SARS-CoV-2 3CLpro main protease.

98%
A290622 现货 Indinavir sulfate/硫酸茚地那韦

Indinavir sulfate is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.

98+%
A1371128 现货 Aescin A/七叶皂苷A

Escin IA is the main active ingredient of the saponin fraction of Aesculus chinensis Bunge fruits (SFAC) for the anti-TNBC metastasis activity, and its action mechanisms involved inhibition of EMT process by down-regulating LOXL2 expression.

98%
A547820 现货 Ritonavir/利托那韦

Ritonavir is both an HIV protease inhibitor and a Cytochrome P450 3A inhibitor.

98%
A924956 现货 7-DIETHYLAMINO-3-THENOYLCOUMARIN

97%
A296461 现货 Rosamultin/罗莎白素

97%
产品名 HIV Protease HIV-1 caspid 其他靶点 纯度
Dextran sulfate sodium, mw 40,000 M.W 40000
Vicriviroc maleate 98+%
Rosamultin 97%
Darunavir 98%
Lopinavir ++++

HIV protease, Ki: 1.3 pM

99+%
Chloroquine Autophagy 95%
Amprenavir +

HIV protease, IC50: 14.6 ng/mL

PXR 99%+
NBD-556 99%+
Nelfinavir Mesylate +++

HIV protease, Ki: 2 nM

99%+
Atazanavir Sulfate 98%
Limonin 98%
Saquinavir ++

HIV proteinase, IC50: 2.7 nM

98%
Ritonavir 98%
Azvudine 98%
Lenacapavir ++++

HIV-1 capsid, EC50: 0.1 nM

97%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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