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货号 产品名 纯度
A1216869 现货 LDN-192960

LDN-192960 是一种双重抑制剂,针对 Haspin 和 DYRK2 IC50 值分别为 10 nM 和 48 nM。

99%+
A1208659 现货 INDY

INDY is inhibitor of DYRK1B and DYRK1A with IC50 values of 0.23 and 0.24 μM respectively.

99%+
A941258 现货 GSK-626616

GSK 626616 is a potent and selective DYRK inhibitor with IC50 of 0.7 nM for DYRK3, similar potency for DYRK1 and 2.

99%
A559999 现货 Neobavaisoflavone/新补骨脂异黄酮

Neobavaisoflavone, an isoflavone isolated from the seeds of Psoralea corylifolia, has striking anti-inflammatory and anti-cancer effects.

99%+
A872532 现货 AZ-Dyrk1B-33

AZ Dyrk1B 33 is a potent and selective ATP-competitive Dyrk1B kinase inhibitor with IC50 of 7 nM.

99%+
A1194998 现货 GNF4877

GNF4877 is a potent DYRK1A and GSK3β inhibitor with IC50s of 6 nM and 16 nM, respectively

99%+
A1365253 现货 T025

98%+
A353812 现货 CLK-IN-T3

Clk inhibitor T3 is a highly selective, stable CLK inhibitor with high specificity to CLK1-3 protein isoforms.

99%+
A1599775 现货 GNF2133

98%+
A404720 现货 AZ191

AZ 191 is a potent and selective DYRK1B inhibitor with IC50 of 17 nM in a cell-free assay, about 5- and 110-fold selectivity over DYRK1A and DYRK2, respectively.

98%
A159775 现货 Isoluminol/异鲁米诺

98%
A861000 现货 ML167

ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, showing > 10-fold selectivity for closely related kinases Clk1-3 and Dyrk1A/1B.

99%+
A1173604 4-(Trifluoromethyl)aniline-d4

98% 98%atom%D
A1249685 FINDY

A1364801 DYRKs-IN-1

98%
A1485291 Woodtide

98%
A1603097 JH-XIV-68-3

98%
A1601924 Dyrk1A-IN-1

98%
A1671567 GNF2133 HCl

98%
A2420195 Dyrk1A-IN-2

98%
产品名 DYRK DYRK1 DYRK2 其他靶点 纯度
ID-8 99%+
AZ191 ++++

DYRK1A, IC50: 88 nM

DYRK1B, IC50: 17 nM

98%
Harmine +++

DYRK1A, IC50: 33 nM

DYRK1B, IC50: 166 nM

++

DYRK2, IC50: 1.9 μM

98%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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