Hemicholinium 3是胆碱转运体（HACU）的竞争性高亲和力抑制剂，其Ki值为25 nM。Hemicholinium 3抑制乙酰胆碱（ACh）的合成和释放，是一种神经肌肉阻滞剂。Hemicholinium 3以897 nM和693 nM的IC50值抑制表皮酸诱导的收缩和乙酰胆碱释放。

Tenuifolin是从远志中提取的三萜类化合物，具有口服活性和神经保护作用。天茄草皂苷通过抑制 β-分泌酶减少 Aβ 蛋白分泌，抑制 Aβ25-35 诱导的凋亡以及 caspase-3 和 caspase-9 激活。

MDH1-IN-2是一种有效且选择性的MDH1抑制剂，其IC50为2.27 μM，具有研究癌症疾病的潜力。

Drofenine HCl is a potent competitive inhibitor of BChE, and the ki values of drofenine is calculated to be 3 μM.

(+)-Pteryxin, a natural product isolated and purified from the herbs of Peucedanum harry-smithii var. subglabrum, has muscle-relaxant property and shows hepatoprotective and nitric oxide prodn. inhibitory activity.

Isomeranzin is a natural product isolated and purified from the peels of Citrus maxima with antimycobacterial activity.

Picfeltarraenin IA, a natural product isolated and purified from the herbs of Picria felterrae Lour., is a stronger AChE inhibitor than the known AChE inhibitor Tacrine, a potential PI3K and epidermal growth factor receptor (EGFR ) inhibitor with anti-inflammatory activity, and acts as an inhibitor on both the classical and alternative pathways of the complement system.

Galantamine is a competitive and reversible cholinesterase (AChE) inhibitor and is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments.

Vasicine, a natural product isolated and purified from the leaves of Adhatoda vasica, is a potential cholinesterase inhibitor in development for treatment of Alzheimer's disease, and can regulate the inflammatory reaction.

Sophoflavescenol is a prenylated flavonol, which shows great inhibitory activity with IC50 of 13 nM against phosphodiesterase 5 (PDE5), and also inhibits RLAR, HRAR, AGE, BACE1, AChE and BChE with IC50s of 0.30 μM, 0.17 μM, 17.89 μg/mL, 10.98 μM, 8.37 μM and 8.21 μM, respectively.

Nodakenin is a natural product isolated and purified from the root of Angelica biserrata (Shan et Yuan) Yuan et Shan. with anti-aggregatory, antibacterial, anti-allergic, anti- inflammator, and memory-enhancing effects.