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货号 产品名 纯度
A957502 现货 KH7

KH7是可溶性腺苷酸环化酶(sAC)的特异性抑制剂,在细胞中对重组sACt蛋白(人类和其他物种)的IC50为3-10 μM。KH7也是cAMP的抑制剂。

99%+
A417613 现货 SQ22536/9-(四氢-2-呋喃)腺膘呤

SQ22536是一种有效的腺苷酸环化酶(AC)抑制剂。

99%+
A204150 现货 2',3'-Dideoxyadenosine/2',3'-二脱氧腺苷

2′,3′-Dideoxyadenosine is a nucleoside analog of deoxyadenosine. It inhibits adenylyl cyclase and may play a key role in the inhibition of tumor progression. It is a potent inhibitor of reverse transcriptase enzyme of HIV.

98%
A1176389 现货 LRE1

97%
A1552289 现货 TDI-10229

98%
A507715 现货 NKY80

95%
A1719720 现货 I942

98%
A168725 现货 PACAP (1-38), human, ovine, rat/PACAP(1-38)游离态

PACAP 1-38 is a potent PACAP receptor agonist with IC50s of 4 nM, 2 nM, and 1 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2 respectively.

98%
A722266 现货 2',5'-Dideoxyadenosine/2',5'-二脱氧腺苷

2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site with an IC50 of 3 µM . 2',5'-Dideoxyadenosine is a nucleoside analog and exerts a potent antiadrenergic action in heart .

99%+
A1475061 现货 LY367385 HCl

95%
A419526 现货 Resveratrol/白藜芦醇

Resveratrol is one of the numerous polyphenolic compounds found in several vegetal sources, has a wide spectrum of targets with IC50 of 0.8, 1, 3.3 and 5 μM for Adenylyl cyclase, IKKβ, DNA polymerase α and δ, respectively.

98%
A226193 现货 Forskolin/毛喉素

Forskolin is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types with binding (IC50=41 nM) to and activation (EC50=0.5 μM) of type I adenylyl cyclase. It is commonly used to raise levels of cAMP in the research of cell physiology.

98%
A138799 现货 Bithionol/硫氯酚

Bithionol is an anti-parasitic drug and can be used to inhibit solid tumor growth in several preclinical cancer models.

98%
A1009869 Adenylyl cyclase-IN-1

95%
A1177463 Small Cardioactive Peptide B (SCPB)

97%
A1209444 Guanylyl Imidodiphosphate trisodium

97%
A1226327 9-Cyclopentyladenine monomethanesulfonate

98%
A1507844 Mant-GTPγS

98%
A1602056 AC1-IN-1

98%
A1671840 Adenylyl cyclase type 2 agonist-1

98%
产品名 AC EPAC1 EPAC2 PACAP receptor 其他靶点 纯度
Bithionol +

sAC, IC50: 4.0 μM

98%
SQ22536 99%+
ESI-09 ++

EPAC1, IC50: 3.2 μM

+++

EPAC2, IC50: 1.4 μM

99%+
HJC0350 +++

EPAC2, IC50: 0.3 μM

97%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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