ABT-737 是一种选择性的 Bcl-2 家族蛋白抑制剂，能够有效抑制 Bcl-2、Bcl-xL 和 Bcl-w 的活性，IC50 值分别为 30.3 nM、78.7 nM 和 197.8 nM。ABT-737 主要用于研究细胞凋亡、抗癌治疗和增强肿瘤对化疗药物的敏感性。

A1331852 is a potent and selective BCL-XL inhibitor and may be useful in the treatment of cancer, immune and autoimmune diseases.

BAX-IN-1是一种潜在的 Bcl-2 相关蛋白 (BAX) 的选择性抑制剂。

HA14-1 inhibits Bcl-2 with IC50 of ~9 μM by binding to the surface pocket and disturb the interaction of Bax/Bcl-2, it's cell-permeable.

Navitoclax (ABT-263) 是一种口服有效的 Bcl-2 抑制剂，可与多种 Bcl-2 家族蛋白结合，Ki 值小于 1 nM。

Sabutoclax is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.

BI-3812 is a BCL6 inhibitor, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM.

CID5721353 is a B-Cell Lymphoma 6 inhibitor (BCL6 inhibitor).

Azoramide is a modulator of the unfolded protein response (UPR) with antidiabetic activity.

A-1210477是一种高效且选择性的 MCL-1 抑制剂，Ki 为 0.45 nM。它特异性结合 MCL-1 并促进依赖 MCL-1 的癌细胞凋亡。

BH3I-1 is an inhibitor of Bcl-xL with IC50 of 293.95 μM.

AT101 acetic acid, the R-(-) enantiomer of gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM.

BTSA1 is a BAX activator that binds to the N-terminal activation site with high affinity and specificity, induces conformational changes to BAX leading to BAX-mediated apoptosis.

Obatoclax, a Bcl-2 homology domain-3 mimetic, antagonize all antiapoptotic Bcl-2 family proteins (average IC50, 3 μMol/L), including Mcl-1 (IC50, 2.9 μMol/L) and Bfl-1 (IC50, 5 μMol/L).

S55746 is a potent and selective inhibitor of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2), with potential pro-apoptotic and antineoplastic activities.

Alisol B is a natural product isolated and purified from the tubers of Alisma plantago-aquatica Linn. for bone disorders by targeting the differentiation of osteoclasts as well as their functions.

MCL-1/BCL-2-IN-2是一种有效的选择性 Mcl-1 和 Bcl-2 抑制剂。

ML311, also known as EU-5346, is a selective inhibitor of the interaction of Mcl-1 and Bim.

Gossypol acetic, a natural product isolated from cottonseeds and roots, binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively.

Bcl-B inhibitor 1是一种选择性的 Bcl-B 蛋白抑制剂，在调节凋亡途径和抗癌药物开发中有重要应用价值。