GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with IC50 of 62 nM.

Galangin functions as an antagonist of the aryl hydrocarbon receptor and also inhibits CYP1A1 (IC50 = 1 μM). It belongs to flavonoids and can be extracted from the rhizome of Zingiber officinale Roscoe with anti-inflammatory properties.

Aryl Hydrocarbon Receptor (AhR) Agonists, Signal Transduction Modulators

Formononetin can act as an agonist of aryl hydrocarbon receptor (EC50 = 130 nM) and has prevention of breast cancer, prostate cancer and colon cancer. Formononetin could be extracted from the bark of Ononis natrix L..

PDM 11 is a derivative of the antioxidant trans-resveratrol.

UM729 是一种新型的嘧啶并吲哚，具有协同作用，作为 AhR 拮抗剂，能够抑制 AML 细胞分化。

StemRegenin 1 是一种有效的芳香烃受体 (AhR) 拮抗剂，IC50 为 127 nM。

Aryl Hydrocarbon Receptor (AhR) Agonists, Signal Transduction Modulators

ITE is an AhR agonist with Ki value of 3nM, and also inhibits TGF-β-induced human myofibroblast differentiation.

CH-223191 是一种强效和特异性的芳香烃受体 (AhR) 拮抗剂。它抑制 TCDD 介导的 AhR 核转位和 DNA 结合，并以 0.03 μM 的 IC50 抑制 TCDD 诱导的荧光素酶活性。