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货号 产品名 纯度
A262784 3-Oxo-5β-cholanoic acid

97%
A1281887 RORγ inverse agonist 1

98%+
A887606 SR2211

SR2211 是一种有效且选择性的 RORγ 合成调节剂,作为反向激动剂,其 Ki 值为 105 nM,IC50 值约为 320 nM。

99%+
A769555 GSK805

GSK805 是一种口服活性 RORγt 抑制剂,能够穿透中枢神经系统。GSK805 抑制 RORγ 和 Th17 细胞分化,其 pIC50 分别为 8.4 和 >8.2。GSK805抑制 Th17 细胞功能,可用于免疫学研究。

98%+
A240693 SR1001

SR1001 is a selective RORα and RORγ inverse agonist and inhibits TH17 cell differentiation and function.

99%+
A576988 GSK2981278

GSK2981278 is a retinoid-related orphan receptor gamma (RORy) modulator.

99%+
A244776 SR-1078

SR-1078 is an agonist of RORα and RORγ and can increase transcriptional activity of RORα with 2 μM.

98+%
A129464 SR3335

SR3335 can selectively bind to RORα and competitively inhibit the binding of 25-hydroxycholesterol to the ligand binding domain with Ki of 220 nM.

98%
A1167892 PF-06747711

PF-06747711 is a potent, selective, and orally active retinoic acid receptor-related orphan C2 (RORC2, also known as RORγt) inverse agonist, with an IC50 of 4.1 nM. Anti-skin inflammatory activity.

99%+
A627902 Cintirorgon

LYC-55716 is agonist of RAR-related orphan receptor γ (RORγ).

99%+
A1176758 RORγt Inverse agonist 2

A1177096 AZD-0284

99.65%
A1246287 RORγt Inverse agonist 8

98%
A1257142 TMP780

98%
A1364838 TMP920

98%
A1553551 RORγ agonist 1

98%
A1602386 RORγt modulator 5

98%
A1601040 Retezorogant

98%
A1603213 RORγt agonist 3

98%
A1680516 RORγt inhibitor 2

98%
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