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全部(267) Agonist(12) Antagonist(11) Inhibitor(3) Activator(2)
p-Hydroxy-cinnamic acid is the isomer of cinnamic acid with anti-mutagenic and anti-tumor activities.
TG4-155是一种有效的穿脑选择性EP2受体拮抗剂,其Ki为9.9 nM。TG4-155仅对EP2和DP1受体显示低纳摩尔级别的拮抗活性。TG4-155对EP2的KB为2.4 nM,显示出对DP1受体的14倍选择性,对EP1、EP3、EP4和IP受体的选择性为550-4750倍。
Ralinepag, is an orally available agonist of the prostacyclin (IP) receptor.
AM211 is a potent and selective prostaglandin D2 receptor type 2 antagonist with IC50 value of 4.9nM.
AH 6809 is an EP and DP receptor antagonist with nearly equal affinity for the cloned human EP1, EP2, EP3-III, and DP1 receptors.
E7046 is a specific antagonist of the type 4 prostaglandin E2 (PGE2) receptor EP4. It possesses significant antitumor growth activity in multiple preclinical tumor models through modulating myeloid cells, including tumor-associated macrophages and myeloid-derived suppressor cells.
Asapiprant is a potent and selective DP1 receptor antagonist with a Ki of 0.44 nM.
Limaprost is a PGE1 analog and potent platelet adhesion inhibitor.
Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent, and is a PGF2α receptor agonist.
Taprenepag is an agonist of prostaglandin E2 receptor with EC50 of 2.8 nM with hypotensive activity.
Licarin A, a natural product isolated and purified from Machilus thunbergii, is a candidate compound for the treatment of immediate hypersensitivity via inhibition of rat mast cell line RBL-2H3 cells.
Laropiprant is a potent, selective DP1 receptor antagonist with Ki value of 0.57 nM and exhibits > 1,000 fold selectivity over DP2 receptor (Ki=0.75 μM).
Treprostinil sodium is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.
Ramatroban is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis.
Tafluprost is an anti-glaucoma prostaglandin (PG) analog.
Tags: 前列腺素受体 | Prostaglandin Receptor | G蛋白偶联受体/G蛋白 | GPCR/G Protein | 前列腺素受体 相关产品
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