Human Wnt3a V3/人Wnt3a V3蛋白(HEK293, tag free)
{[allProObj[0].p_purity_real_show]}
货号：A2900913同义名：
重组人Wnt3a V3蛋白(HEK293, tag free)
/ Recombinant Human Wnt3a V3; Wnt Surrogate-Fc Fusion Protein
Recombinant Human Wnt3a V3是人类重组Wnt3a蛋白V3版本，在人源细胞中表达，无标签。该蛋白属于脊椎动物Wnt家族，是高度保守的富含半胱氨酸的分泌型糖蛋白，参与正常发育过程，调控多个重要器官与组织的发育、稳态及再生，包括骨、肝、皮肤、中枢神经系统等，具有治疗退行性疾病和组织损伤的潜力，可通过FZD和LRP受体传递信号。
Human Wnt3a V3/人Wnt3a V3蛋白(HEK293, tag free) 化学结构 CAS号：N/A
Human Wnt3a V3/人Wnt3a V3蛋白(HEK293, tag free) 3D分子结构 CAS号：N/A
Wnt-3a is one of 19 vertebrate members of the Wingless-type MMTV integration site (Wnt) family of highly conserved cysteine-rich secreted glycoproteins important for normal developmental processes. WNT signaling plays key roles in the control of development, homeostasis, and regeneration of many essential organs and tissues, including bone, liver, skin, stomach, intestine, lung, kidney, central nervous system, mammary gland, taste bud, ovary, cochlea, and vessels among many others. Modulation of WNT signaling pathways has potential for treatment of degenerative diseases and tissue injuries. And they signal through FZD1-10 and LRP5 or 6, two families of receptors. Endogenous WNTs bind to multiple FZDs and are heavily modified posttranslationally, making them difficult to manufacture consistently. WNT surrogate molecules phenocopied endogenous ligand activities in in vitro reporter assays and intestine organoid functional assays. WNT surrogate molecules can be selective for individual FZD or a subfamily of FZDs in combination with LRP5 or LRP6, depending on the binder specificities.
蛋白种属
Human
表达系统
Human cells
内毒素
< 0.01 EU/µg as determined by LAL test.
剂型
液体
剂型描述
Supplied as a 0.2 μm filtered solution of 25mM Tris-HCl, 500mM NaCl, pH8.2.
重组人Wnt3a V3蛋白(HEK293, tag free)
;Recombinant Human Wnt3a V3; Wnt Surrogate-Fc Fusion Protein; Wnt Surrogate
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
最近浏览的产品
Tags:
Human Wnt3a V3/人Wnt3a V3蛋白(HEK293, tag free)
|Human Wnt3a V3/人Wnt3a V3蛋白(HEK293, tag free)
| 重组人Wnt3a V3蛋白(HEK293, tag free)
| Recombinant Human Wnt3a V3
| Wnt Surrogate-Fc Fusion Protein
| Wnt Surrogate
| N/A
| Other Cytokines and Growth Factors
| 干细胞诱导
| Human Wnt3a V3/人Wnt3a V3蛋白(HEK293, tag free) 纯度/质量文件
| Human Wnt3a V3/人Wnt3a V3蛋白(HEK293, tag free) 生物活性
| Human Wnt3a V3/人Wnt3a V3蛋白(HEK293, tag free) 技术信息
搜索
