Human Wnt3a V3
产品说明书
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同义名 : | 重组人Wnt3a V3蛋白(HEK293, tag free) ;Recombinant Human Wnt3a V3 |
| CAS号 : | N/A | |
| 货号 : | A2900913 | |
| 分子式 : | - | |
| 纯度 : | 95% >=95% as determined by reducing SDS-PAGE. | |
| 分子量 : | 0 | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -70°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
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| 描述 | 产品名称：Recombinant Human Wnt3a V3理论分子量：58.5kDa蛋白种属：Human表达系统：Human cells蛋白表达区间：0标签：0剂型：液体纯度：≥95% as determined by reducing SDS-PAGE.储存条件：储存温度≤-70°C，收到后可稳定保存1年。 储存于≤-70°C，开封后在无菌条件下可稳定保存3个月。 开封后请按照用量分装，尽量减少反复冻融次数。产品背景：Wnt-3a is one of 19 vertebrate members of the Wingless-type MMTV integration site (Wnt) family of highly conserved cysteine-rich secreted glycoproteins important for normal developmental processes. WNT signaling plays key roles in the control of development, homeostasis, and regeneration of many essential organs and tissues, including bone, liver, skin, stomach, intestine, lung, kidney, central nervous system, mammary gland, taste bud, ovary, cochlea, and vessels among many others. Modulation of WNT signaling pathways has potential for treatment of degenerative diseases and tissue injuries. And they signal through FZD1-10 and LRP5 or 6, two families of receptors. Endogenous WNTs bind to multiple FZDs and are heavily modified posttranslationally, making them difficult to manufacture consistently. WNT surrogate molecules phenocopied endogenous ligand activities in in vitro reporter assays and intestine organoid functional assays. WNT surrogate molecules can be selective for individual FZD or a subfamily of FZDs in combination with LRP5 or LRP6, depending on the binder specificities. | ||