Human PDGF-BB (E.coli)/人PDGF-BB蛋白(Tag free, E.coli)
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货号：A2924152同义名：
重组人PDGF-BB蛋白(Tag free, E.coli)
/ Recombinant Human PDGF-BB (E.coli); PDGFBB
Recombinant Human PDGF-BB (E.coli) 是人源血小板衍生生长因子亚基B（PDGFB）重组蛋白，在大肠杆菌中表达，无标签。该蛋白属于PDGF/VEGF生长因子家族，是间充质来源细胞的有效有丝分裂原，可形成同源二聚体PDGF-BB，与受体结合后能促进细胞增殖，参与伤口修复和组织再生，其基因突变与脑膜瘤相关。
Human PDGF-BB (E.coli)/人PDGF-BB蛋白(Tag free, E.coli) 化学结构 CAS号：N/A
Human PDGF-BB (E.coli)/人PDGF-BB蛋白(Tag free, E.coli) 3D分子结构 CAS号：N/A
Human PDGF-BB (E.coli)/人PDGF-BB蛋白(Tag free, E.coli) 质控信息
Human PDGF-BB (E.coli)/人PDGF-BB蛋白(Tag free, E.coli) 生物活性
描述
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc, pH 4.5.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human PDGF-BB (E.coli)/人PDGF-BB蛋白(Tag free, E.coli) 技术信息
CAS号
N/A
分子量
12.42 KDa
SMILES Code
NONE
别名
重组人PDGF-BB蛋白(Tag free, E.coli)
;Recombinant Human PDGF-BB (E.coli); PDGFBB; PDGF-BB
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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