Human PDGF-BB (E.coli)
产品说明书
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同义名 : | 重组人PDGF-BB蛋白(Tag free, E.coli) ;Recombinant Human PDGF-BB (E.coli); PDGFBB; PDGF-BB |
| CAS号 : | N/A | |
| 货号 : | A2924152 | |
| 分子式 : | - | |
| 纯度 : | 98% determined by reducing SDS-PAGE. | |
| 分子量 : | 12.42 KDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. | ||