货号:A701706
同义名:
乙醇酸
/ Hydroxyethanoic acid; dicarbonous acid
Glycolic Acid是最小的α-羟基酸,因其出色的皮肤渗透性,常用于化学去角质护肤品中。
HazMat Fee + There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
| Type | HazMat fee for 500 gram (Estimated) |
| Excepted Quantity | USD 0.00 |
| Limited Quantity | USD 15-60 |
| Inaccessible (Haz class 6.1), Domestic | USD 80+ |
| Inaccessible (Haz class 6.1), International | USD 150+ |
| Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
| Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |


| 规格 | 价格 | 会员价 | 库存 | 数量 | |||
|---|---|---|---|---|---|---|---|
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快速发货 顺丰冷链运输,1-2 天到达
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免费溶解

| 产品名称 | diphenolase ↓ ↑ | monophenolase ↓ ↑ | tyrosinase ↓ ↑ | 其他靶点 | 纯度 | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hexylresorcinol |
+++
diphenolase, IC50: 0.85 μM |
++
monophenolase, IC50: 1.24 μM |
+++
monophenolase, IC50: 0.85 μM diphenolase, IC50: 0.85 μM |
99%+ | |||||||||||||||
| Aloin | ✔ | 98% (mixture of A&B) | |||||||||||||||||
| Arbutin |
+
tyrosinase, IC50: 1.09 mM |
98% | |||||||||||||||||
| Monobenzone | ✔ | 98% | |||||||||||||||||
| Deoxyarbutin |
++++
tyrosinase, IC50: 50 nM |
98% | |||||||||||||||||
| 1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。 | |||||||||||||||||||
| Concentration | Treated Time | Description | References | |
| Mouse embryonic cortical neurons | 2.5×10⁻³, 5×10⁻³, 10×10⁻³, 20×10⁻³ M | Immediately after 1 hour of ischemia | To determine the neuroprotective properties of GA during ischemia-reperfusion damage. Results showed that GA treatment significantly reduced necrotic and apoptotic neuronal death, with the strongest effect observed at 20×10⁻³ M. | Adv Sci (Weinh). 2022 Feb;9(4):e2103265 |
| Administration | Dosage | Frequency | Description | References | ||
| Mice | Global cerebral ischemia (GCI) and middle cerebral artery occlusion (MCAO) models | Intra-carotid injection (GCI model), intraperitoneal injection (MCAO model) | 120×10⁻³ M (GCI model), 60 mg/kg (MCAO model) | Single injection (GCI model), immediately after operation until day 3 (MCAO model) | To evaluate the protective effects of GA against ischemic damage in vivo. Results showed that GA treatment significantly increased neuronal survival, reduced infarct volume, and improved functional recovery. | Adv Sci (Weinh). 2022 Feb;9(4):e2103265 |
| 计算器 | ||||
| 存储液制备 | ![]() |
1mg | 5mg | 10mg |
|
1 mM 5 mM 10 mM |
13.15mL 2.63mL 1.31mL |
65.75mL 13.15mL 6.57mL |
131.49mL 26.30mL 13.15mL |
|
| CAS号 | 79-14-1 |
| 分子式 | C2H4O3 |
| 分子量 | 76.05 |
| SMILES Code | O=C(O)CO |
| MDL No. | MFCD00004312 |
| 别名 | 乙醇酸 ;Hydroxyethanoic acid; dicarbonous acid; Glycollic acid; hydroacetic acid; hydroxyacetic acid |
| 运输 | 蓝冰 |
| InChI Key | AEMRFAOFKBGASW-UHFFFAOYSA-N |
| Pubchem ID | 757 |
| 存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 |
| 溶解方案 |
DMSO: 105 mg/mL(1380.65 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 100 mg/mL(1314.9 mM),配合低频超声助溶 以下溶解方案都请先按照体外实验的方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议现用现配,当天使用; 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶
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