Ambeed.cn

首页 / / / / Braco-19

Braco-19 {[allProObj[0].p_purity_real_show]}

货号:A1365648

Braco-19是一种端粒酶/端粒抑制剂,通过稳定四联体 (GQ) 结构来阻断端粒酶的催化作用,导致快速细胞衰老或选择性细胞死亡。此外,Braco-19 也

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Braco-19 化学结构 CAS号:351351-75-2
Braco-19 化学结构
CAS号:351351-75-2
Braco-19 3D分子结构
CAS号:351351-75-2
Braco-19 化学结构 CAS号:351351-75-2
Braco-19 3D分子结构 CAS号:351351-75-2
规格 价格 会员价 库存 数量
{[ item.pr_size ]}

{[ getRatePriceInt(item.pr_rmb, 1,1) ]}

{[ getRatePriceInt(item.pr_rmb_sale, 1,1) ]} {[ suihuo_tips(item.pr_tag_price, item.pr_am) ]}

{[ getRatePriceInt(item.pr_rmb, 1,1) ]}

{[ getRatePriceInt(item.pr_rmb,item.pr_rate,1) ]} {[ suihuo_tips(item.pr_tag_price, item.pr_am) ]}
{[ getRatePriceInt(item.pr_rmb, 1,1) ]}{[ suihuo_tips(item.pr_tag_price, item.pr_am) ]} {[ getRatePrice(item.pr_rmb_sale, 1,1,item.mem_isinteger) ]} {[ getRatePrice(item.pr_rmb,item.pr_rate,item.mem_rate,item.mem_isinteger) ]} {[ getRatePrice(item.pr_rmb,1,item.mem_rate,item.mem_isinteger) ]} 现货 1周 咨询 - +
购物车0 收藏 询单

Braco-19 纯度/质量文件 产品仅供科研

货号:A1365648 标准纯度: {[allProObj[0].p_purity_real_show]}
批次查询: 批次纯度:

全球学术期刊中引用的产品

Nature, 2025, 645, 793-800. Ambeed. [ A201204 , A444152 , A344107 , A952055 ]
Cell, 2025. Ambeed. [ A122167 ]
Science, 2025, 387(6729): eadp5637. Ambeed. [ A875019 ]
Sig. Transduct. Target. Ther., 2025, 10, 257. Ambeed. [ A104916 ]
Nat. Nanotechnol., 2025. Ambeed. [ A243018 , A1216705 , A522597 , A125401 , A1355641 ]
更多 >
产品名称 DNA synthesis helicase RdRp ribonucleotide reductase tRNA synthetase YB-1 其他靶点 纯度
Fexinidazole 98%
Daptomycin 98%
Blasticidin S·HCl 98%
Metronidazole 98%
Daunorubicin HCl +++

DNA synthesis, Ki: 20 nM

98%
Triglycidyl isocyanurate p53 98+%
Nedaplatin 99%+
Oxolinic acid 98+%
Bendamustine 98+%
Trifluridine 98%
Robinetin 99%+
Carboplatin 99%
Cidofovir 99%
Cisplatin 99%
Cytarabine ++++

DNA synthesis, IC50: 16 nM

98%
Acelarin ++++

DNA synthesis, EC50: 0.2 nM

99%+
Oxaliplatin 98%
YK-4-279 99%+
ML216 +

BLMfull-length, IC50: 2.98 μM

BLM636-1298, IC50: 0.97 μM

99%+
RK-33 98%
Brr2-IN-3 99%+
Phen-DC3 Trifluoromethanesulfonate 95%
Favipiravir 99%
Suramin sodium salt ++

RdRp, IC50: 0.26 μM

99%+
Clofarabine ++

Ribonucleotide reductase, IC50: 65 nM

97%
Didox 98%
(E)-3-AP 99%
Halofuginone +++

prolyl-tRNA synthetase, Ki: 18.3nM

99%+
BC-LI-0186 +++

Leucyl-tRNA synthetase, IC50: 46.11 nM

Leucyl-tRNA synthetase, Kd: 42.1 nM

98%
SU056 +

YB-1, IC50: 1.73 μM

98%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。

Braco-19 细胞实验

Cell Line
Concentration Treated Time Description References
Human adipose-derived mesenchymal stem cells (ASCs) 0.15 to 10 µM 13 days To evaluate the effect of Braco-19 on ASC differentiation into adipocytes, results showed that Braco-19 at non-cytotoxic concentrations induced morphological changes in mature adipocytes partially restoring an undifferentiated-like status, and reduced lipid accumulation and PPARG, AP2, LEP mRNA levels. Stem Cell Res Ther. 2023 Apr 19;14(1):98
U2OS cells 1 μM 48 h To evaluate the effect of BRACO-19 on HHV-6A integration frequency, results showed BRACO-19 had no significant effect on HHV-6A integration frequency in U2OS cells J Virol. 2017 Jun 26;91(14):e00402-17
MCF-7 cells 1 μM 48 h To evaluate the effect of BRACO-19 on HHV-6A integration frequency, results showed BRACO-19 significantly reduced HHV-6A integration frequency J Virol. 2017 Jun 26;91(14):e00402-17
HeLa cells 1 μM 48 h To evaluate the effect of BRACO-19 on HHV-6A integration frequency, results showed BRACO-19 significantly reduced HHV-6A integration frequency J Virol. 2017 Jun 26;91(14):e00402-17
Vero cells 1 μM to 25 μM To evaluate the anti-HSV-1 activity of BRACO-19, results showed significant antiviral effects at 1 μM, with up to 70% inhibition at 25 μM Antiviral Res. 2015 Jun;118:123-31

Braco-19 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.68mL

0.34mL

0.17mL

8.42mL

1.68mL

0.84mL

16.84mL

3.37mL

1.68mL

Braco-19 技术信息

CAS号351351-75-2
分子式C35H43N7O2
分子量 593.76
SMILES Code CN(C)C1=CC=C(C=C1)NC2=C3C=CC(NC(CCN4CCCC4)=O)=CC3=NC5=CC(NC(CCN6CCCC6)=O)=CC=C52
MDL No. MFCD23380200
别名
运输蓝冰
存储条件

In solvent -20°C: 3-6个月 -80°C: 12个月

Pure form Keep in dark place, inert atmosphere, 2-8°C

溶解方案

DMSO: 35 mg/mL(58.95 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

请根据您的动物给药指南选择适当的溶解方案。
以下溶解方案都请先按照体外实验的方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议现用现配,当天使用; 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶
方案 一
方案 二
AmBeed 相关网站 AmBeed.cn AmBeed.com
AmBeed
关于我们
联系我们
资讯中心
网站地图
产品手册
  • 批次文件查询
  • 客户支持
    技术支持
    专业术语
    缩略词释义
    质量手册
    产品咨询
    计算器
    活动政策
    订购方法
    积分商城
    活动声明
    联系我们
    400-920-2911 sales@ambeed.cn tech@ambeed.cn
    AmBeed 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务,不为任何个人或者非科研性质用途提供服务。