NSC756093是一种GBP1:PIM1 相互作用抑制剂。NSC756093 也可用于卵巢癌研究。

SMI-4a is a potent inhibitor of Pim1 with IC50 of 17 nM, modestly potent to Pim-2, does not significantly inhibit any other serine/threonine- or tyrosine-kinases.

SGI-1776 free base is an ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin.

HJ-PI01 (10-Acetylphenoxazine)是一种口服活性的 Pim-2 抑制剂，能诱导癌细胞凋亡和自噬性细胞死亡，并抑制 MDA-MB-231 异种移植小鼠肿瘤生长。HJ-PI01 可用于癌症研究。

Pim-1/2 kinase inhibitor 1是一种口服有效的 Pim-1/2 激酶抑制剂，用于抑制癌症，尤其是前列腺癌的研究。

(2R)-Octyl-α-hydroxyglutarate是 2-羟基戊二酸 (2-HG) 的 D 型异构体的修饰物，常用于研究代谢调控以及 2-HG 在肿瘤代谢中的角色，特别是在 IDH 突变相关的癌症中。

CX-6258 HCl is a potent, orally efficacious pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3, respectively.

CX-6258 is a selective and potent Pim inhibitor with IC50 values of 5nM, 25nM and 16nM for Pim-1, Pim-2 and Pim-3 (measured by SAR assay), respectively.

TCS PIM-1 1 is a potent and selective ATP-competitive Pim-1 kianse inhibitor with IC50 of 50 nM, displays good selectivity over Pim-2 and MEK1/MEK2 (IC50s > 20,000 nM).

SMI-16a, the PIM1/2 Kinase inhibitor VI, controls the biological activity of PIM1/2. This small molecular inhibitor is primarily used for Phosphorylation & Dephosphorylation applications

TP-3654 is a selective Pim kinase inhibitor with Ki values of 5nM, 239nM and 42nM for Pim-1, Pim-2 and Pim-3, respectively, as well as with an average EC50 of 67nM for cellular PIM-1 inhibition in the PIM-1/BAD overexpression system and with moderate potency to FLT3.

AZD1208 is an orally bioavailable, highly selective PIM kinases inhibitor with single nanomolar potency against all three PIM kinases (IC50 of 0.4 nM, 5 nM, and 1.9 nM for Pim1, Pim2, and Pim3 in cell-free assays, respectively) and is used for treating AML.

PIM-447 is pan-PIM kinase inhibitor, including Moloney Murine Leukemia (PIM)1, 2, and 3 Kinase.

Hispidulin, a natural product isolated and purified from the herbs of Ambrosia artemisiifolia Linn., is a Pim-1 inhibitor with an IC50 of 2.71 μM.

Quercetagetin (6-Hydroxyquercetin) 是一种黄酮类化合物，作为一种中度强效且选择性的细胞可渗透 pim-1 激酶抑制剂，IC50 为 0.34 μM。它具有抗炎和抗肿瘤活性。