Evaluate the effect of Quercetagetin on NHL cell proliferation, showing significant toxicity on OCI-Ly19 cells
Mol Cancer. 2015 Dec 8;14:205.
SUDHL6 cells
SUDHL6 cells
Evaluate the effect of Quercetagetin on NHL cell proliferation, showing anti-proliferative effects on SUDHL6 cells
Mol Cancer. 2015 Dec 8;14:205.
OCI-Ly10 cells
OCI-Ly10 cells
Evaluate the effect of Quercetagetin on NHL cell proliferation, showing anti-proliferative effects on OCI-Ly10 cells
Mol Cancer. 2015 Dec 8;14:205.
OCI-Ly3 cells
OCI-Ly3 cells
Evaluate the effect of Quercetagetin on NHL cell proliferation, showing anti-proliferative effects on OCI-Ly3 cells
Mol Cancer. 2015 Dec 8;14:205.
Ramos cells
Ramos cells
Evaluate the effect of Quercetagetin on NHL cell proliferation, showing anti-proliferative effects on Ramos cells
Mol Cancer. 2015 Dec 8;14:205.
Raji cells
Raji cells
Evaluate the effect of Quercetagetin on NHL cell proliferation, showing anti-proliferative effects on Raji cells
Mol Cancer. 2015 Dec 8;14:205.
JB6 P+ cells
JB6 P+ cells
Inhibited UVB-induced AP-1 and NF-κB transactivation
J Mol Biol. 2013 Jan 23;425(2):411-23.
Huh7.5 cells
Huh7.5 cells
Evaluate the inhibitory effect of Quercetagetin on HCV genotype 2a infectious strain replication, showing dose-dependent inhibition
Nucleic Acids Res. 2014 Aug;42(14):9399-409.
Huh7.5 cells
Huh7.5 cells
Western blot analysis showed Quercetagetin dose-dependently inhibited NS5B protein expression
Nucleic Acids Res. 2014 Aug;42(14):9399-409.
Huh7.5 cells
Huh7.5 cells
Evaluate the inhibitory effect of Quercetagetin on HCV genotype 1b subgenomic replicon replication, showing dose-dependent inhibition
Nucleic Acids Res. 2014 Aug;42(14):9399-409.
H9c2 cardiomyoblasts
H9c2 cardiomyoblasts
To investigate the inhibitory effects of Quercetagetin on LPS-induced MAPK phosphorylation and COX-2 expression in H9c2 cells. Results showed that Quercetagetin significantly inhibited LPS-induced phosphorylation of ERK1/2, p38, and JNK, and reduced COX-2 expression.
Cell Mol Biol Lett. 2017 Sep 4;22:19.
bone marrow-derived monocytes (BMMs)
bone marrow-derived monocytes (BMMs)
To evaluate the inhibitory effect of Quercetagetin on LPS-induced osteoclast differentiation. Results showed that 2 µM Quercetagetin significantly inhibited LPS-driven osteoclast differentiation and function.
Arthritis Res Ther. 2025 Mar 8;27(1):54.
Caco-2/TC7 cells
Caco-2/TC7 cells
To evaluate the inhibitory ability of Quercetagetin on human α-glucosidases (sucrase, maltase, and isomaltase). Results showed that quercetagetin was the strongest inhibitor of α-glucosidases among the tested flavonols, with inhibition constants approaching those of acarbose.
Foods. 2021 Aug 20;10(8):1939.
Quercetagetin/栎草亭 动物实验
Species
Animal Model
Administration
Dosage
Frequency
Description
References
SKH-1 hairless mice
Two-stage skin carcinogenesis model
Topical application
4 or 20 nmol
Significantly inhibited UVB-induced skin cancer development, reduced tumor incidence and volume
J Mol Biol. 2013 Jan 23;425(2):411-23.
DBA/1 male mice
Collagen antibody-induced arthritis (CAIA) model
Intraperitoneal (IP) injection
40 mg/kg
Once daily until day 13
To validate the therapeutic effect of Quercetagetin in the CAIA model. Results showed that 40 mg/kg Quercetagetin significantly alleviated joint destruction and inflammation.
Arthritis Res Ther. 2025 Mar 8;27(1):54.
Rabbits
ZEN-induced liver injury model
Oral
100 mg/kg
28 days
To assess the alleviative effect of quercetagetin (QG) on zearalenone (ZEN)-induced liver injury in rabbits. Results showed that QG alleviated the ZEN-induced oxidative damage and liver injury caused by inflammatory reaction through the Keap1-Nrf2-ARE signal pathway.
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