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货号 产品名 纯度
A263533 现货 Biricodar/比立考达

Biricodar, a non-macrocyclic pipecolinate derivative, is multidrug resistance inhibitor.

95%
A178453 现货 Dofequidar

Dofequidar is a quinoline compound, which can reverse P-glycoprotein (P-gp)-mediated MDR.

98%
A272992 现货 Zosuquidar 3HCl/唑喹达三盐酸盐

Zosuquidar 3HCl(LY335979) 三盐酸盐是一种P-糖蛋白P-gp)抑制剂,Ki值为59 nM。它具有抗肿瘤活性,可用于急性髓性白血病(AML)的研究。

99%+
A658719 现货 Encequidar

HM30181 is a potent and selective inhibitor of P-glycoprotein.

95+%
A351095 现货 Elacridar/依克立达

Elacridar是一种口服活性 P-糖蛋白 (Pgp) 和乳腺癌耐药蛋白 (BCRP) 抑制剂,用于研究外排转运蛋白对药物在脑中分布的影响,并用于癌症研究。

99%+
A1006566 现货 RCGD423

RCGD423 is a gp130 modulator, which prevents articular cartilage degeneration and promotes repair.

97%
A670924 现货 GP130 receptor agonist-1

gp130-agonist-2 is a brain penetrant gp130 agonist which protects against NMDA-induced toxicity and increases STAT3 phosphorylation.

99%+
A251517 现货 Tariquidar/他立喹达

Tariquidar is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM, reverses drug resistance in MDR cell Lines.

98%
A356248 现货 Sinapine thiocyanate/芥子碱硫氰酸盐

Sinapine, an alkaloid isolated and purified from the seeds of Raphanus sativus L., possess antioxidant and radio-protective activities, downregulats multi-drug resistance 1 (MDR1) expression.

99%+
A458424 现货 Schisandrin/五味子醇甲

Schizandrin is a natural product possessing antioxidant and anti-inflammatory activities.

98%
A397520 现货 Chrysosplenetin/猫眼草黄素

Chrysosplenetin, a natural product isolated and purified from the herbs of Laggera pterodonta, is a metabolic inhibitor of artemisinin.

98%
A265225 现货 Isosinensetin/异橙黄酮

Isosinensetin exhibits HIV-1 protease inhibiting and antioxidant activities. It is a natural product isolated and purified from the fruit of Citrus aurantium L..

99%+
A536549 现货 Sinapine/芥子碱

Sinapine 是从十字花科种子中分离出来的生物碱,具有抗炎、抗氧化、抗肿瘤、抗血管生成和放射保护活性。它也是乙酰胆碱酯酶AChE)抑制剂,可用于研究阿尔茨海默病、共济失调、重症肌无力和帕金森病。

99%+
A620428 现货 Wilforine/雷公藤次碱

Wilforine is a natural product isolated and purified from the vines of Tripterygium wilfordii, with insecticidal activity by inhibiting the Na+-K+-ATPase in the central nervous system, and anti-inflammatory effect, which might be mediated by down-regulation of the expression of inflammatory factors TNF-α,IL-6 and NO.

98+%
A1176616 Reversan

97%
A1177698 MCI826

99+%
A1176545 P-gp inhibitor 1

98%
A1176952 P-gp modulator 1

95%
A1176445 TTT-28

99+%
A1210798 MC70

97%
产品名 P-gp 其他靶点 纯度
Elacridar BCRP 99%+
Zosuquidar 3HCl ++

P-gp, Ki: 60 nM

99%+
SC144 99%+
Tariquidar +++

P-gp, Kd: 5.1 nM

98%
Schizandrin B 98%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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