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货号 产品名 纯度
A432274 现货 PEAQX

PEAQX 是一种强效且口服活性的 NMDA 拮抗剂,对人 NMDA 受体的 1A/2A(IC50 = 270 nM)具有 15 倍的优先性,而对 1A/2B 的 IC50 为 29,600 nM。

98%
A194394 现货 Dizocilpine maleate/地卓亚平马来酸盐

Dizocilpine maleate (MK-801 maleate)是一种高效、选择性和非竞争性的NMDA受体拮抗剂,在大鼠脑膜中的Kd为37.2 nM。

99%+
A542047 现货 (-)-Dizocilpine maleate

(-)-Dizocilpine maleate ((-)-MK-801 maleate) 是 Dizocilpine 的活性较低的 (-)-对映体。它是一种选择性、非竞争性的 NMDA 受体拮抗剂,Ki 为 211.7 nM,具有抗抑郁作用。

98%
A188283 现货 NMDA/N-甲基-D-天冬氨酸

NMDANMDA 受体的特异性激动剂,模拟正常作用于该受体的神经递质谷氨酸的作用。

98%
A1144572 现货 Crocetin disodium/藏红花酸钠盐

Trans-crocetin sodium, also known as Transcrocetinate sodium or Sodium crocetinate, is potentially for the treatment of glioblastoma. Trans-crocetin improves amyloid-β degradation in monocytes from Alzheimer's Disease patients. trans-crocetin inhibit glutamatergic synaptic transmission in rat cortical brain slices. Crocetin inhibits invasiveness of MDA-MB-231 breast cancer cells via downregulation of matrix metalloproteinases.

97%
A615114 现货 Oxysophoridine/氧化槐定碱

Oxysophoridine is a natural product isolated and purified from the herb of Sophora alopecuroidos L. Oxysophoridine inhibited N-methyl-D-aspartate NR1 mRNA and protein expression in the cerebral cortex of mice with cerebral ischemia/reperfusion injury.

98%
A637947 现货 Felbamate/非尔氨酯

Felbamate is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA) .

98%
A611376 现货 Memantine/3,5-二甲基金刚胺

Memantine is the first in a class of Alzheimer's disease medications acting on the glutamatergic system by blocking NMDA receptors.

97%
A528436 现货 Kynurenic acid sodium/犬尿喹啉酸钠盐

Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also a selective ligand of the GPR35 receptor.

98%
A737321 现货 1-Aminocyclobutane-1-carboxylic Acid/1-氨基环丁甲酸

1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist acting at the glycine site, NR1.

95%
A146840 现货 6-Methoxy-2-naphthoic acid/6-甲氧基-2-萘甲酸

6-Methoxy-2-naphthoic acid is an modulator of NMDAR.

97%
A545278 现货 MDL-29951

MDL-29951 is a glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo.

99%+
A881153 现货 Spermidine HCl/三盐酸亚精胺

Spermidine, a precursor of spermine, is a polyamine derived from putrescine and could help stabilize some membranes and nucleic acid structures.

99+%
A307218 现货 Mephenesin/甲酚甘油醚

Mephenesin is a centrally acting muscle relaxant which may work as an NMDA receptor antagonist.

95%
A709210 现货 Rislenemdaz

Rislenemdaz, also known as MK-0657, is a NR2B-selective NMDA antagonist potentially for the treatment of Parkinson's disease.

98%
A187972 现货 Budipine/布地平

Budipine is an uncompetitive NMDAR antagonist used as an antiparkinson agent.

99%+
A119976 现货 Rapastinel/雷帕替奈

Rapastinel is a putative NMDAR functional glycine-site partial agonist.

99%+
A1155096 现货 NMDAR antagonist 1

NMDAR antagonist 1 is a NR2B-selective NMDAR antagonist.

98%+
A569101 现货 7-Chlorokynurenic Acid

7-Chlorokynurenic acid is an antagonist of NMDA receptor acting at the glycine site. It can also act as competitive inhibitor of L-glutamate transport into synaptic vesicles.

98%
A393098 现货 CIQ

CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit.

99%
产品名 NMDA receptor 其他靶点 纯度
Empirical Formula 97%
Dizocilpine maleate +++

NMDA receptor, Kd: 37.2 nM

99%+
Felbamate +

NMDAR, IC50: 1.8 mM

98%
(-)-Dizocilpine maleate ++++

NMDA receptor, Ki: 30.5 nM

98%
Ifenprodil tartrate +++

NMDA Receptor, IC50: 0.3 μM

98%
Spermidine Autophagy 98% GC
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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