SB 218795是一种有效的选择性非肽 NK3 受体拮抗剂，对 hNK3 的 Ki 值为 13 nM，其对 hNK3 的选择性比 hNK2 和 hNK1 高 90 倍和 7000 倍。它能抑制 NK3 受体介导的兔瞳孔收缩。

Neurokinin A TFA是速激肽家族中的一种肽类神经递质，通过 NK-2 受体在气道和胃肠道组织中起作用，主要作为神经传递和局部介质调控。

[Sar9,Met(O2)11]-Substance P TFA是一种选择性的 NK1 受体激动剂，适用于神经递质和疼痛机制的研究，特别是在炎症和中枢神经系统疾病中的应用广泛。

Substance P(1-7) TFA是神经肽 P 物质 (SP) 的片段，具有抑制和缓解孤束核的作用。

Elinzanetant是一种口服选择性的 NK-1 和 NK-3 受体拮抗剂，主要用于治疗血管舒缩症状及精神疾病的研究，特别是在潮热和精神分裂症方面表现出潜在的临床应用价值。

SB-222200 is a selective, reversible and competitive antagonist of human NK-3 receptor (Ki=4.4 nM) that effectively crosses the blood-brain barrier.

Tradipitant is the 2nd generation neurokinin-1 receptor antagonist, which showed activity in preclinical anxiety models.

Fezolinetant is Neurokinin-3 (NK-3) receptor antagonist.

Substance P TFA (Neurokinin P TFA) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R)[1].

L-732138 is a potent and highly selective competitive tachykinin NK1 receptor antagonist with IC50 of 2.3 nM.

Aprepitant is a selective and high-affinity neurokinin-1 receptor antagonist with IC50 of 0.1 nM.

Netupitant a potent and highly selective NK1 receptor antagonist with Ki of 0.95 nM.

Maropitant is a neurokinin (NK1) receptor antagonist.

Substance P (Neurokinin P) 是一种神经肽，在中枢神经系统中作为神经递质和神经调节剂。Substance P 的内源性受体是神经激肽1受体 (NK1R)。

Fosaprepitant Dimeglumine is a prodrug for aprepitant which is a selective and high-affinity antagonist of NK1 receptor.

Rolapitant inhibits CYP2D6, breast cancer resistance protein (BCRP), and Neurokinin (NK)1 Receptor.