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货号 产品名 纯度
A1682395 现货 Insulin degludec

Insulin degludec是一种超长效胰岛素,能够持续稳定地降低血糖水平,用于糖尿病管理研究。

98%
A328045 现货 D-(+)-Sorbose

D-(+)-Sorbose是一种D-山梨糖的活性对映异构体,能够有效抑制双糖酶活性,并减少大鼠餐后血糖和胰岛素水平,具有防治2型糖尿病等代谢性疾病的潜力。

95%
A835518 现货 Peonidin 3-O-glucoside chloride/氯化葡萄糖苷芍药素

Peonidin 3-O-glucoside chloride是一种花青素类化合物,能够作为胰岛素促分泌剂,促进HepG2细胞对葡萄糖的摄取。该化合物在2型糖尿病及其并发症的研究中具有潜在应用价值。

97%
A1230191 现货 Ceritinib D7

Ceritinib D7是一种选择性、口服有效且具有ATP竞争性的ALK酪氨酸激酶抑制剂,适用于ALK相关的癌症治疗研究。

95%
A899724 现货 Tolazamide/甲磺氮草脲

Tolazamide is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity.

99%+
A318812 现货 MSDC 0160/米格列酮

MSDC-0160 is a prototype mTOR-modulating insulin sensitizer being studied to treat diabetes and Alzheimer's disease.

99%+
A126440 现货 Ceritinib/色瑞替尼

Ceritinib(LDK378)是一种选择性、口服可用的、ATP竞争性的ALK酪氨酸激酶抑制剂,IC50为200 pM。Ceritinib(LDK378)还以8、7和23 nM的IC50值抑制IGF-1R、InsR和STK22D。Ceritinib(LDK378)显示出强大的抗肿瘤活性。

98%
A361478 现货 BMS-536924

BMS-536924 is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM.

98%
A139562 现货 Linsitinib

Linsitinib(OSI-906)是一种高效、选择性和口服可用的IGF-1受体和胰岛素受体(IR)的双重抑制剂,IC50分别为35 nM和75 nM。

99%+
A462988 现货 NVP-AEW541

NVP-AEW541 (AEW541) 是一种口服活性的胰岛素样生长因子 1 受体 (IGF-1R) 抑制剂,IC50 为 0.15 μM。它还抑制胰岛素受体 (InsR),IC50 为 0.14 μM,显示出显著的抗肿瘤活性。

99%+
A135758 现货 Cinnamic acid/肉桂酸,只含反式

Cinnamic acid can stimulate insulin secretion and improve glucose tolerance.

98% only trans
A184967 现货 BMS-754807

BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM, less potent to Met, Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc.

99%+
A330186 现货 Rhoifolin/野漆树苷

Rhoifolin, a natural product isolated and purified from the leaves of Turpinia arguya Seem, hows monolithic proliferation inhibitory activities against Hela, A549 and MCF-7 cell lines, and may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4. It was found to efficiently block the enzymatic activity of SARS-CoV 3CLpro.

99%+
A224689 现货 Kaempferitrin/山奈苷

Kaempferitrin can activate insulin signaling pathway, phosphorylate Akt kinase and exert the transloocation of GLUT4, thus has antitumor, antidepressant and antidiabetic effects. Kaempferitrin is a natural product isolated and purified from the root of Kaempferia galangal L..

95%
A1163884 GIP, human/抑胃肽

Gastric Inhibitory Peptide (GIP), human is thought to act as an inhibitor of gastric functions. It also affects lipid metabolism and displays mitogenic and antiapoptotic effects in pancreatic β-cells.

99%
A1209494 HNMPA

97%
A1209951 HNMPA-(AM)3

97%
A1256703 (Pro3) GIP, human

98+%
A1256512 GIP (1-30) amide,human

A1256666 GIP (3-42), human

95%
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