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货号 产品名 纯度
A800214 现货 Windorphen

Windorphen 是一种 Wnt/β-catenin信号抑制剂,选择性靶向 β-catenin-1 的 C 末端转录激活域,而不靶向 β-catenin-2。Windorphen 选择性破坏哺乳动物 β-catenin 与 p300 的关联,而不影响 CBP。

95%
A1489779 现货 PF-9363

PF-9363 (CTx-648) 是一种高效且选择性的 KAT6A/KAT6B 抑制剂,可用于癌症研究。

99%+
A146696 现货 ICG-001

ICG-001是一种β-连环蛋白/TCF介导转录的抑制剂,通过特异性结合环AMP反应元件结合蛋白IC50为3 μM,选择性阻断β-连环蛋白/CBP相互作用,而不影响β-连环蛋白/p300相互作用。

99%+
A608814 现货 Forodesine/呋咯地辛

Forodesine (BCX-1777) 是一种有效的口服活性嘌呤核苷磷酸化酶 (PNP) 抑制剂,对人、小鼠、大鼠、猴和狗的 PNPIC50 值范围为 0.48 到 1.57 nM。

99%
A1176639 现货 GNE-781

GNE-781 是一种有效、口服活性和选择性的 CBP 抑制剂,在 TR-FRET 测定中的 IC50 为 0.94 nM。GNE-781 还抑制 BRET 和 BRD4 (1),IC50 值分别为 6.2 nM 和 5100 nM。

98%
A1671105 现货 NSC 694623

98%
A2626744 现货 JG-2016

98%
A1210995 现货 TTK21

97%
A1483452 现货 PU139

99%+
A2250228 现货 KAT6-IN-1

98%
A314356 现货 CTPB

99%
A1359463 现货 NEO2734

NEO2734 is an orally dual p300/CBP and BET bromodomain inhibitor with IC50 values of <30 nM for both p300/CBP and BET bromodomains.

99%+
A1365010 现货 CBP/p300-IN-3

98%
A190197 现货 Anacardic Acid/漆树酸

Anacardic acid is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases, which also has antibacterial activity, antimicrobial activity,prostaglandin synthase inhibition, and tyrosinase and lipoxygenase inhibition.

99%+
A479140 现货 Histone Acetyltransferase Inhibitor II/组蛋白乙酰转移酶抑制剂II

Histone Acetyltransferase inhibitor II, insulin producing cells capable of secreting blood glucose regulating hormones, specially insulin, in response to physiological signals, method of production of said cells and uses thereof.

99%+
A171428 现货 Remodelin HBr

Remodelin hydrobromide is a selective inhibitor of acetyl-transferase protein NAT10.

99%+
A122218 现货 C646

C646 is a selective inhibitor of histone acetyltransferase p300 with Ki of 400 nM.

99%+
A573581 现货 WM-1119

MOZ-IN-1 is an inhibitor of MOZ which is a member of histone acetyltransferases with IC50 of 0.051 μM.

99%+
A691133 现货 Remodelin

Remodelin is a potent and selective inhibitor of the acetyl-transferase protein NAT10.

99%+
A732746 现货 A-485

A 485 is a potent and selective p300/CREB-binding protein (CBP) HAT domain inhibitor with IC50 of 2.6 and 9.8 nM for the CBP-bromodomain HAT-C/H3 (BHC) and p300-BHC domains, respectively.

99%+
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