CP-640186 is an isozyme-nonselective acetyl-CoA carboxylase (ACCase) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively with improved metabolic stability vs CP-610431.

Acetyl-CoA Carboxylase-IN-1是一种有效的乙酰辅酶 A 羧化酶 (ACC) 抑制剂，IC₅₀ 值为小于 5 nM。它具有抗菌活性，适用于研究脂肪酸代谢途径及其在病原体中的作用，可用于抗菌药物的开发。

PF-05175157 is a potent and selective ACC inhibitor with IC50 values of 27nM and 33nM for ACC1 and ACC2, respectively.

ND-646 is an allosteric inhibitor of the ACC enzymes ACC1 and ACC2 that prevents ACC subunit dimerization-to suppress fatty acid synthesis in vitro and in vivo. Chronic ND-646 treatment of xenograft and genetically engineered mouse models of NSCLC inhibited tumor growth.

TOFA is a potent, reversible and competitive acetyl-CoA carboxylase (ACC) inhibitor which can inhibit fatty acid synthesis.

PF-05221304 是一种口服可生物利用的，肝靶向的 acetyl-CoA carboxylase (ACC) 的抑制剂，是一种催化脂肪从头生成(DNL)的第一步的酶。

ND-630 is an allosteric inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits ACC1 and ACC2 activity (IC50s = 2.1 and 6.1 nM, respectively, for the human enzymes).

CP-640186 HCl is a metabolic stability improved ACC inhibitor with IC50 values of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2,respectively.