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货号 产品名 纯度
A334893 现货 Fluxametamide/氟甲酰胺

Fluxametamide 是一种广谱杀虫剂和 GABA 及谷氨酸门控氯离子通道拮抗剂,其对 M. domestica 中的 GABACl 和 GluCl 的 IC50 值分别为 1.95 nM 和 225 nM。

99%+
A724974 现货 Fluralaner

Fluralaner (INN) 是一种全身性杀虫剂和杀螨剂,通过强效阻断 GABA 和 L-glutamate氯离子通道发挥作用。

98%
A1209836 现货 Eact

Eact is an activator of TMEM16A calcium-activated chloride channel (CaCC) with EC50 of 3 μM. It is also transient receptor potential vanilloid 1 (TRPV1) channel activator (EC50 = 11.6 μM).

99%+
A385750 现货 NS1652

NS1652 is a reversible anion conductance inhibitor, blocks chloride channel, with an IC50 of 1.6 μM in human and mouse red blood cells.

99%+
A886198 现货 R(+)-Methylindazone

R(+)-IAA-94 is a potent indanyloxyacetic acid blocker of epithelial chloride channels.

99%+
A648561 现货 T16Ainh-A01

T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC).

99%+
A109193 现货 Selamectin/塞拉菌素

Selamectin is an avermectin derivative prepared by hydrolysis and oximation of doramectin. Selamectin is a potent nematocide used for the treatment of parasites, which selectively binds to parasite glutamate-gated chloride ion channels and disrupts neurotransmission.

95%
A336852 现货 NPPB/5-硝基-2-(3-苯丙胺)苯甲酸

NPPB can act as a blocker of the chloride channel with IC50 of 100 nM-100 µM and inhibitor of cyclooxygenase (IC50 = 8 µM).

99%+
A1176584 现货 DCPIB

99%
A1671166 现货 ANO1-IN-1

98%+
A1213607 现货 Afoxolaner

99%+
A207771 现货 Niflumic Acid/氟尼酸

Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.

98%
A288138 现货 (Rac)-Shikonin/莽草素

99%
A706788 现货 Shikonin/紫草素

Shikonin is an inhibitor of TMEM16A chloride channel with IC50 of 6.5 μM, it's a natural product isolated and purified from the roots of Lithosperraum erythrorhizon Sieb. et Zucc..

99%+
A1157109 现货 Emidurdar

Endovion is a blocker of both VRAC and CaCC with IC50 value around 400nM for blocking swelling-activated anion currents in HEK293 cells.

97%
A119156 现货 Anthracene-9-carboxylic acid/9-蒽甲酸

9-AC is a Cl- transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac IcI.

98%
A1602484 DFBTA

98%
A1938697 BTG 1640

98%
A1269507 Flufenamic acid-13C6

98% +98%atom%13C
A1671179 ANO1-IN-2

98%
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