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BL-918 is an orally active UNC-51-like kinase 1 (ULK1) activator with an EC50 of 24.14 nM. BL-918 induces cytoprotective autophagy for Parkinson's disease treatment.
LK-101 is a potent and selective ULK1 inhibitor with in vitro IC50 of 8.3 nM.
SBI-0206965是一种高效、选择性、细胞渗透性 ULK1 激酶抑制剂,对 ULK1 激酶的 IC50 为 108 nM,对密切相关的激酶 ULK2 的 IC50 为 711 nM。
MRT68921 是一种有效的 ULK1 和 ULK2 抑制剂,IC50 值分别为 2.9 nM 和 1.1 nM。
LYN-1604 is a potent UNC-51-like kinase 1 (ULK1) agonist with an EC50 of 18.94 nM.
MRT68921 HCl is a selective inhibitor of ULK1 and ULK2 with IC50 0f 2.9 nM and 1.1 nM.
MRT68921 dihydrochloride is the most potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively.
LYN-1604 HCl is an agonist of ULK1 with EC50 of 18.94 nM.
MRT67307 HCl is a potent and dual IKKε and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively.
LYN-1604 dihydrochloride is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC)[1].
MRT67307 HCl is a potent and dual IKKε and TBK1 inhibitor.
Tags: ULK | 自噬 | Autophagy | ULK 相关产品
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