Fatostatin HBr (125B11 hydrobromide)专门抑制SREBP的激活，阻止SREBP-1和SREBP-2的激活。它结合到SCAP（SREBP裂解激活蛋白）并阻止SREBPs的ER-高尔基体转运，减少细胞中脂质生成基因的转录。法托司汀溴化物表现出抗肿瘤特性，并减少ob/ob小鼠的高血糖。

Fatostatin (125B11) 是一种特异性抑制SREBP激活的抑制剂，阻止SREBP-1和SREBP-2的激活。它与SCAP（SREBP裂解激活蛋白）结合，抑制SREBPs的ER-高尔基体转运，减少细胞中脂质生成基因的转录。Fatostatin具有抗肿瘤特性，并降低ob/ob小鼠的高血糖。

Pseudoprotodioscin，一种呋喃葡糖苷，抑制 SREBP1/2 和 microRNA 33a/b 水平，降低胆固醇和甘油三酯合成相关的基因表达。

Praeruptorin D, a natural product isolated and purified from the roots of Peucedanum praeruptorum Dunn., can significantly inhibit the infiltration of activated polymorphonuclear leukocytes (PMNs) and decrease the levels of TNF-α and IL-6 in bronchoalveolar lavage fluid at the same dose, suppresses LPS induced Nuclear Factor-kappa B (NF-κB) pathway activation in the lung by decreasing the cytoplasmic loss of inhibitor κB-α (IκB-α) protein and inhibiting the translocation of p65 from cytoplasm to nucleus.

PF429242 2HCl is a reversible and competitive SREBP site 1 protease (S1P) inhibitor with IC50 value of 175nM.

Cinobufotalin is one of the bufadienolides prepared from toad venom with anticancer activity.