There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
To evaluate the effects of Upamostat and Opaganib on cell viability and migration in the cholangiocarcinoma cell line HuCCT1. Results showed that both WX-UK1 and Opaganib individually and in combination led to cell growth regression and reduced migration.
Cancers (Basel). 2024 Mar 5;16(5):1050
Upamostat 动物实验
Species
Animal Model
Administration
Dosage
Frequency
Description
References
Nude mice
Cholangiocarcinoma patient-derived xenograft model (PAX165)
Oral gavage
70 mg/kg Upamostat, 50 mg/kg Opaganib
Once daily for 6 weeks
To evaluate the effects of Upamostat and Opaganib, alone or in combination, on tumor growth in a cholangiocarcinoma xenograft model. Results showed that both Upamostat and Opaganib significantly inhibited tumor growth, with a more pronounced effect when used in combination.
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