There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
(R)-Flurbiprofen is the R-enantiomer of the racemate NSAID flurbiprofen, inhibiting the binding of [3H]9-cis-RA to RXRαLBD with IC50 of 75 μM.
Tarenflurbil/R-氟比洛芬 动物实验
Species
Animal Model
Administration
Dosage
Frequency
Description
References
Mice
Tg2576 transgenic mice
Oral
10 mg/kg/day
Once daily for 4 months (preventative treatment) or 2 weeks (therapeutic treatment)
To evaluate the effect of R-flurbiprofen on cognitive function and Aβ load in Tg2576 mice. Preventative treatment improved spatial learning but did not significantly reduce Aβ load; therapeutic treatment significantly reduced Aβ plaque burden but did not improve spatial learning.
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