There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Salicylanilide demonstrates a wide range of biological activities including antiviral potency which can inhibit HIV virus by targeting HIV-1 integrase or reverse transcriptase[3]. Salicylanilide derivatives substituted by halogens on both salicyl and aniline rings showed better activity, than 4-benzoylaniline derivatives. The ester or carbamate bond formation of parent salicylanilides mostly retained or improved antimycobacterial potency with moderate selectivity[4]. Salicylanilide was excreted unchanged (56%) with small amounts of the 5-hydroxy and 4'-hydroxy-derivatives[5].
Salicylanilide/水杨酰苯胺 细胞实验
Cell Line
Concentration
Treated Time
Description
References
MOLM-13 R248Q
5.9 µM (IC50)
72 hours
To evaluate the anti-proliferative effect of NCL on MOLM-13 R248Q cells, showing an IC50 of 5.9 uM, indicating lower sensitivity of this mutant cell line to NCL compared to WT cells.
Leukemia. 2024 Jul;38(7):1630-1633
MOLM-13 KO
1.9 µM (IC50)
72 hours
To evaluate the anti-proliferative effect of NCL on MOLM-13 KO cells, showing an IC50 of 1.9 uM, indicating higher sensitivity of KO cells to NCL.
Leukemia. 2024 Jul;38(7):1630-1633
MOLM-13 WT
2.6 µM (IC50)
72 hours
To evaluate the anti-proliferative effect of NCL on MOLM-13 WT cells, showing an IC50 of 2.6 uM.
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